Mindfulness-Oriented Recovery Enhancement for Addictive Behavior, Psychiatric Distress, and Chronic Pain: A Multilevel Meta-Analysis of Randomized Controlled Trials.

Mindfulness (N Y)

Center On Mindfulness and Integrative Health Intervention Development, University of Utah, 395 South, 1500 East, Salt Lake City, UT 84112 USA.

Published: September 2022

AI Article Synopsis

  • Mindfulness-Oriented Recovery Enhancement (MORE) is an intervention aimed at reducing addiction, chronic pain, and psychiatric issues, and this study conducted a meta-analysis to evaluate its effectiveness across various randomized controlled trials (RCTs).
  • The analysis included findings from 16 manuscripts covering 8 RCTs with a total of 816 participants, showing moderate to small positive effects of MORE on addictive behaviors, cravings, opioid usage, chronic pain, and psychiatric symptoms.
  • The results indicate that MORE is beneficial for a diverse range of individuals, suggesting it should be widely implemented in healthcare settings.

Article Abstract

Objectives: Mindfulness-Oriented Recovery Enhancement (MORE) is an integrative intervention designed to ameliorate addiction, chronic pain, and psychiatric symptoms. Although multiple randomized controlled trials (RCTs) have examined the clinical efficacy of MORE, no study has quantitatively synthesized this body of research. Thus, we conducted a meta-analysis of RCTs examining the effects of MORE on addictive behaviors, craving, opioid dose, pain, and psychiatric symptoms.

Methods: Relevant manuscripts were identified through comprehensive searches of four bibliographic databases. Two- and three-level random-effects models were used to generate synthesized effect size estimates, and meta-regressions were performed to examine whether study and sample characteristics influenced the magnitude of aggregate effect sizes.

Results: Our search identified 16 manuscripts reporting data from eight RCTs ( = 816). Moderate to small effects in favor of MORE were observed for addictive behaviors (SMC =  - .54,  = .007), craving (SMC =  - .42,  = .010), opioid dose (MC =  - 17.95,  < .001), chronic pain (SMC =  - .60,  < .001), and psychiatric symptoms (SMC =  - .34,  < .001). MORE's effects on psychiatric symptoms and craving were not moderated by participant race, gender, age, or income.

Conclusions: Study findings provide empirical evidence of MORE's efficacy for a wide diversity of individuals, and as such, MORE should now be disseminated broadly throughout the healthcare system.

Supplementary Information: The online version contains supplementary material available at 10.1007/s12671-022-01964-x.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476401PMC
http://dx.doi.org/10.1007/s12671-022-01964-xDOI Listing

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