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Anti-lipoprotein lipase antibodies: A review.
Autoimmun Rev
January 2025
Serviço de Reumatologia, Hospital Universitário Evangélico Mackenzie, Curitiba, PR, Brazil.
Background: Dyslipidemia is described in several autoimmune conditions. Lipoprotein lipase (LPL) is responsible for triglyceride breakdown. Anti-LPL antibodies have been described.
View Article and Find Full Text PDFAnti-Lipoprotein Lipase Antibody as a Useful Marker for Plaque Vulnerability in Patients with Stable Angina.
J Atheroscler Thromb
July 2024
Department of Biomedical Informatics, Division of Health Sciences, Osaka University Graduate School of Medicine.
Aims: Identifying patients with vulnerable plaque who have poor prognosis among those with coronary artery disease (CAD) is crucial to deciding future therapeutic interventions. We previously reported that male CAD patients with low anti-apolipoprotein B-100 autoantibody (anti-apoB-100 Ab) levels were at an increased risk of developing unstable plaque lesions. This study focused on the autoantibodies against lipoprotein lipase (LPL), a key enzyme in triglyceride metabolism, which is another risk factor for atherosclerosis, and investigated their association with plaque characteristics.
View Article and Find Full Text PDFUnusual Manifestation of Dermatomyositis: Exacerbation of Hypertriglyceridemia.
Cureus
December 2023
Department of Diabetes, Metabolism and Endocrinology, Japanese Red Cross Akita Hospital, Akita, JPN.
Systemic lupus erythematosus is known to cause autoimmune hyperlipidemia. We present a case in which hypertriglyceridemia was exacerbated by dermatomyositis. A 53-year-old woman with a medical history of undertreated hypertriglyceridemia complained of dyspnea and arthralgia.
View Article and Find Full Text PDFAnti-lipoprotein lipase antibody-associated autoimmune hypertriglyceridaemia in a patient with systemic lupus erythematosus.
Lupus
October 2022
Department of Endocrinology, 12887Metabolism and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan.
Juvenile dermatomyositis: is periodontal disease associated with dyslipidemia?
Adv Rheumatol
September 2018
Pediatric Rheumatology Unit, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Rua Joel Jorge de Melo, 600 apto 121, Vila Mariana, São Paulo, SP, 04128-081, Brazil.
Background: Association between periodontal disease and dyslipidemia was recently reported in healthy adults. However, a systematic evaluation of concomitant periodontal diseases and lipid profile was not carried out in juvenile dermatomyositis (JDM). A cross-section study was performed in 25 JDM patients and 25 healthy controls, assessing demographic data, periodontal evaluation, fasting lipoproteins and anti-lipoprotein lipase antibodies.
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