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Investigating the efficacy of gellan gum hydrogel films infused with Acacia stingless bee honey in wound healing.
Int J Biol Macromol
January 2025
Faculty of Science and Marine Environment, Universiti Malaysia Terengganu, 21030, Terengganu, Malaysia. Electronic address:
Effective wound healing requires biocompatible and functional wound dressings. This study explores the synergistic potential of gellan gum (GG), known for its exceptional gel-forming abilities, and acacia stingless bee honey (SBH), for its potent antioxidant properties, in developing advanced wound care solutions. GG hydrogel films incorporated with varying concentrations of SBH (v/v) at 10 % (GGSBH10), 15 % (GGSBH15), and 20 % (GGSBH20) were characterized.
View Article and Find Full Text PDFExpediting acute wound healing by integrating multiple therapeutic strategies: a case series.
Wound Manag Prev
December 2024
Acute Surgical Wound Service, Department of Surgery, Christiana Care, Newark, DE; Department of Surgery, Christiana Care, Newark, DE.
Background: Traumatic injuries have increased risks for infection and progression to difficult-to-heal wounds. Often, they are inadequately treated with single-purpose dressings. Involving wound care specialists allows for integrating various advanced wound treatments.
View Article and Find Full Text PDFSuspect dyskeratotic neoformations in a 7-year-old child with keratitis-ichthyosis-deafness syndrome: diagnostic, surgical and wound care management.
Dermatol Reports
November 2024
Plastic Surgery Unit, Department of Neuroscience, University of Padua.
Keratitis-ichthyosis-deafness syndrome (KID) is a rare genetic disorder characterized by the triad of hyperkeratosis, ichthyosis, and congenital prelingual sensorineural deafness, with less than 100 cases described in the literature. In addition to many other extra-cutaneous manifestations, these patients are burdened by two principal increased risk factors involving the skin: the risk of developing infections and the risk of developing malignant skin tumors, especially Squamous Cell Carcinoma and Trichilemmal tumors. We present the case of a 7-year-old girl with a unique genetic variant described to date, who developed 4 dyskeratotic neoformation.
View Article and Find Full Text PDF[Ulcers and diabetic foot : Modern and alternative treatment strategies].
Dermatologie (Heidelb)
January 2025
Colentina Klinik, Dermatologie 2, "Carol Davila" Universität für Medizin und Pharmazie, Bukarest, Rumänien.
Treatment of diabetic foot is challenging due to the complex pathophysiological mechanisms, various clinical manifestations, severe complications with considerable impairment of quality of life, and the need for special, individualized treatment strategies. Particularly in the case of diabetic foot ulcers, conventional therapies are not always effective, so new treatment strategies are needed. This review aims to present alternative therapies with current efficacy data for diabetic foot ulcers that may be suitable for treatment-refractory ulcers.
View Article and Find Full Text PDFJanus Films Wound Dressing Comprising Electrospun Gelatin/PCL Nanofibers and Gelatin/Honey/Curcumin Thawed Layer.
ACS Appl Bio Mater
December 2024
Caspian Faculty of Engineering, College of Engineering, University of Tehran, Rezvanshar, Guilan 43861-91836, Iran.
A promising approach for wound treatment is using multilayer wound dressings that offer multifunctional properties. In this study, a bilayered electrospun/hydrogel gelatin-based scaffold integrated with honey and curcumin was developed to treat wounds under an in vivo study. The first layer consisted of an enzymatic cross-linked gelatin hydrogel containing honey and curcumin, which gelatin/PCL nanofibers reinforced.
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