Effect of and extracts on and : An study.

Objective: Current therapy strategies of leishmaniasis have some problems such as high cost, toxicity and side effects. Plant extracts can be a source of drugs to control leishmaniasis. In this study, the effect of hydroalcoholic and chloroformic extracts of , and on and was studied.

Methods: The plant samples were collected from west of Iran and their extracts were prepared. Anti-promastigote activity assay of all extracts was done using tetrazolium-dye assay.

Results: Only high concentrations of and were able to inhibit , while both high and low concentrations of had antileishmanial effect. No difference was observed between hydroalcoholic with chloroformic extract of each plant.

Conclusion: Altogether, the results revealed the antileishmanial activity of extracts against and , indicating its potential as an antileishmanial agent.