The authors report the case of a 42-year-old female with history of type I diabetes mellitus and recent episode of diabetic ketoacidosis who presented with symptoms of epistaxis, gastrointestinal upset, hyperglycemia, confusion, and a cough. She was found to have rhino-cerebral mucormycosis with associated multi-focal strokes and a left internal carotid artery pseudoaneurysm. Her infection was successfully treated with dual-antifungal therapy consisting of liposomal amphotericin B and isavuconazole, and required only minimal surgical debridement.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9474854PMC
http://dx.doi.org/10.1016/j.idcr.2022.e01615DOI Listing

Publication Analysis

Top Keywords

rhino-cerebral mucormycosis
8
minimal surgical
8
surgical debridement
8
successful treatment
4
treatment rhino-cerebral
4
mucormycosis dual
4
dual antifungal
4
antifungal therapy
4
therapy minimal
4
debridement authors
4

Similar Publications

Background: Mucormycosis, is a rare yet potentially life-threatening fungal infection common in immunocompromised patients. Despite optimal care, mucormycosis in haemato-oncological patients often results in poor outcomes. This case series details the presentations and unique challenges faced during the management of patients with acute myeloid leukemia who developed rhino-cerebral mucormycosis.

View Article and Find Full Text PDF

Opportunistic fungal infections are associated with patients having compromised systemic health. In India, a slow rise in cases of mucormycosis has been observed as the country has seen a rising number of diabetes mellitus cases in the recent decades. This apart, an enormous increase in case numbers was seen in association with COVID-19 infections in the Asian subcontinent, Southeast Asia, markedly in India.

View Article and Find Full Text PDF

Epidemiological Trends of Mucormycosis in Europe, Comparison with Other Continents.

Mycopathologia

November 2024

Fourth Department of Internal Medicine, General University Hospital "Attikon", National and Kapodistrian University of Athens, 12462, Athens, Greece.

Article Synopsis
  • * The incidence in developed countries is relatively low (0.06 to 0.3 cases per 100,000), but in India, it spikes to about 14 cases per 100,000, making it significantly more prevalent there than in Europe, where rates range from 0.04 to 0.12.
  • * Diabetes mellitus is the most common risk factor globally for mucormycosis, with varying patterns; in Europe, hematological cancers are more prevalent, while the disease often appears in patients
View Article and Find Full Text PDF

Background: Mucormycosis, also known as black fungus, is a rare but serious fungal infection caused by mucor that belongs to Zygomycotic species. Mucor is characterized by non-septate, irregularly wide hyphae with right-angle branching. Mucor can infect different systems of the body and manifest differently depending on the location of the infection, which includes pulmonary, gastrointestinal, rhino-cerebral, and cutaneous.

View Article and Find Full Text PDF
Article Synopsis
  • * The condition can manifest in different forms, with a notable case involving pulmonary mucormycosis combined with an aspergillus infection in an immunocompromised patient.
  • * The patient, suffering from metastatic prostate cancer and receiving chemotherapy, was initially misdiagnosed as having only an aspergillus infection before the correct diagnosis of pulmonary mucormycosis was made.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!