Synchronous Oral and Breast Malignancies: A Rare Presentation.

Multiple malignancies may represent metastasis from one location to another or independent primary tumors. The distinction is important because the prognosis and treatment are different. Existence of two malignancies having different histopathologies at anatomically distinct sites is a rare event to occur in an individual. We present one such unusual case of a 40-year-old Indian woman who presented with left breast lump along with a simultaneously occurring growth floor of the mouth. Fine needle aspiration cytology and histopathology revealed features of infiltrating ductal carcinoma breast and adenoid cystic carcinoma of floor of the mouth. This rare organ combination was further managed by surgery and chemo-radiation. To the best of our knowledge, this is the first documentation in the world literature of such a presentation.