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The regulatory function of spp. on the immune inflammatory response in the gut microbiome. | LitMetric
spp. is a unicellular organism that resides in digestive tract of various vertebrates, with a worldwide distribution and a variable prevalence. For many years, spp. was considered a cyst of a flagellate, a fungus, or a saprophyte yeast of the digestive tract; in 1996, it is placed in the group of stramenopiles (heterokonts). Since its new classification, many questions have arisen around this protist about its role as a pathogen or non-pathogen organism. Recent evidence indicates that spp. participates in the immune inflammatory response in the intestinal microbiome generating an anti-inflammatory response, showing a lower concentration of fecal inflammatory markers in infected human hosts. Here, we review recent findings on the regulatory function of spp. in the immune inflammatory response to comprehend the purpose of spp. in health and disease, defining if spp. is really a pathogen, a commensal or even a mutualist in the human gut microbiome.
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