Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420308 | PMC |
http://dx.doi.org/10.1016/j.ajem.2022.08.028 | DOI Listing |
Background: Understanding the fundamental differences between the human and pre-human brain is a prerequisite for designing meaningful models and therapies for AD. Expressed CHRFAM7A, a human restricted gene with carrier frequency of 75% in the human population predicts profound translational significance.
Method: The physiological role of CHRFAM7A in human brain is explored using multiomics approach on 600 post mortem human brain tissue samples (ROSMAP).
Alzheimers Dement
December 2024
University of Pittsburgh, Pittsburgh, PA, USA.
Background: The COVID-19 pandemic had a major impact on healthcare, contributing to a mass exodus of the workforce. This poses a concern for Alzheimer's disease and related dementias (ADRD) care, which benefits from consistent care routine and staff that know the resident. Therefore, it is important to understand nursing home staff perspectives on maintaining high staff morale, which impacts recruitment, retention, and care quality.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Pittsburgh Alzheimer's Disease Research Center (ADRC), Pittsburgh, PA, USA.
Background: Black and African American adult males have the worst overall health than any other race or gender in the United States. The rate of Alzheimer's Disease is twice as high for Black and African American adults. Yet, little is known about how Black and African American adult males perceive the relationship between the social determinants of health and Alzheimer's Disease.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Kentucky, Lexington, KY, USA.
Background: Emerging research suggests that complementary and supportive care programs, such as music therapy, show positive short-term impacts (e.g., purposeful engagement, positive emotions) on persons with dementia who live in care facilities.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Kansas Alzheimer's Disease Research Center, Fairway, KS, USA.
Background: Latinx individuals bear a disproportionate burden of Alzheimer's disease and related dementias (ADRD), with higher risk, underdiagnosis, and limited access to quality care. Primary care providers (PCPs) are crucial for early detection and management, yet organizational and policy factors significantly impact their ability to provide culturally competent and equitable ADRD care for this community. This study explores PCP perspectives to inform the development of accessible models that improve early diagnosis, preventive care, and quality of life for Latinx individuals with ADRD.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!