AI Article Synopsis
- - Ten new flavonoids, called denticulains A-J, were discovered in the plant Macaranga denticulata, along with seven previously known flavonoids.
- - The structures of these compounds were determined using advanced techniques and by comparing them with existing data.
- - Two specific compounds (denticulain A and another known flavonoid) showed the ability to inhibit cancer cell growth in lab tests, with respective IC values of 46.08 μM and 56.83 μM.
Article Abstract
Ten new prenylated flavonoids, named denticulains A-J (1-10), together with seven known prenylated flavonoids (11-17) were isolated from Macaranga denticulata. Their structures were elucidated on the basis of detailed spectroscopic analysis and by comparison with literature data. In addition, compounds 1 and 14 inhibited the proliferation of SW620 and HCT-116 cell lines with an IC value of 46.08 μM and 56.83 μM, respectively.
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| http://dx.doi.org/10.1016/j.fitote.2022.105302 | DOI Listing |
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