In this issue of Cell Chemical Biology, Vijayan and colleagues identify host factors integral for Plasmodium liver-stage infection using a whole-genome CRISPR-Cas9 knockout screen. Their efforts reveal that liver-stage parasites redistribute host microtubules to the parasite membrane in a process dependent on the host Golgi.
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| http://dx.doi.org/10.1016/j.chembiol.2022.08.005 | DOI Listing |
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Knowledge, Attitudes, and Practices of Senior Dental Clinicians of a Dental College in Manila on the Use of International Caries Detection and Assessment System (ICDAS).
Acta Med Philipp
November 2024
College of Dentistry, University of the Philippines Manila.
Objectives: This study aims to establish baseline data on the knowledge, attitudes, and practices (KAP) of senior dental clinicians, which may help determine areas of ICDAS that could be reinforced in teaching, training, and open opportunities for future studies in the Philippines.
Methods: A quantitative descriptive study design used a 4-part online questionnaire for senior dental clinicians from A.Y.
Finding predictive factors of exercise adherence in randomized controlled trials on low back pain: an individual data re-analysis using machine learning techniques.
Arch Phys Med Rehabil
January 2025
Institute of Occupational, Social and Environmental Medicine, Goethe University Frankfurt. Electronic address:
Objective: To identify predictors of adherence in supervised and self-administered exercise interventions for individuals with low back pain.
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Development of dual polymerase spiral reaction for detection of Listeria monocytogenes and Staphylococcus aureus simultaneously.
Int J Food Microbiol
January 2025
College of Food Science and Engineering, Nanjing University of Finance and Economics, Nanjing, China. Electronic address:
Listeria monocytogenes and Staphylococcus aureus are prevalent foodborne pathogens responsible for poisoning humans with food. The present study was devoted to the establishment of a method based on dual polymerase spiral reaction (dual-PSR) and melting curve analysis for concurrent identification L. monocytogenes and S.
View Article and Find Full Text PDFKDM6A facilitates Xist upregulation at the onset of X inactivation.
Biol Sex Differ
January 2025
Department of Laboratory Medicine and Pathology, School of Medicine, University of Washington, Seattle, WA, 98195, USA.
Background: X chromosome inactivation (XCI) is a female-specific process in which one X chromosome is silenced to balance X-linked gene expression between the sexes. XCI is initiated in early development by upregulation of the lncRNA Xist on the future inactive X (Xi). A subset of X-linked genes escape silencing and thus have higher expression in females, suggesting female-specific functions.
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