The history of computing usually focuses on achievements in Western universities and research centers and is mostly about what happened in the United States and Great Britain. However, in Eastern Europe, particularly in war-torn Poland, where there was very little state funding, many highly original hardware and software projects were initiated. The small number of publications available to us, especially those in English, led to the belief that technological progress was the result of research carried out in Western countries alone. This article aims to fill this knowledge gap by focusing on the numerous research projects initiated in Polish universities and computer industries that unfortunately turned into dead ends as the result of socialist policies. These are references that cannot be ignored, not only for a historical reconstruction of the evolution of technology but also with regard to the social effects recorded in Poland immediately after the Second World War. The communist ideology, which pursued gender equality policies after the end of the war, encouraged women to pursue education, enabling the many female students enrolled in mathematics degree courses to specialize in "" (mathematical machines) and become, like men, experts in computer programming and design. As well as highlighting the role that Poland played in the nascent "computer science" and providing detailed information on what women contributed, this article will explain why the success of the Polish computer industry was limited due to the nonexistent coordination between the communist states (Comecon).
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http://dx.doi.org/10.1177/00732753221121502 | DOI Listing |
Circ Cardiovasc Qual Outcomes
January 2025
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor. (C.C., L.B.M., L.D.L.).
Background: Few population-based studies have assessed sex differences in stroke recurrence. In addition, contributors to sex differences in recurrence and poststroke mortality, including social factors, are unclear. We investigated sex differences in these outcomes and the contribution of social, clinical, and behavioral factors to the sex differences.
View Article and Find Full Text PDFCureus
December 2024
General Surgery, Bashair Teaching Hospital, Khartoum, SDN.
Aim The aim is to audit the documentation process for trauma patients presenting to the surgical trauma department and to implement the WHO Standardized Emergency Unit Form: Trauma at Bashair Teaching Hospital in Khartoum, Sudan, in 2022. Methodology The audit was commenced by reviewing the documentation method for trauma patients. There was no standardized form in use.
View Article and Find Full Text PDFJ Zhejiang Univ Sci B
October 2024
Department of Thoracic Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Hexavalent chromium Cr(VI), as a well-established carcinogen, contributes to tumorigenesis for many human cancers, especially respiratory and digestive tumors. However, the potential function and relevant mechanism of Cr(VI) on the initiation of esophageal carcinogenesis are largely unknown. Here, immortalized human esophageal epithelial cells (HEECs) were induced to be malignantly transformed cells, termed HEEC-Cr(VI) cells, via chronic exposure to Cr(VI), which simulates the progress of esophageal tumorigenesis.
View Article and Find Full Text PDFJ Zhejiang Univ Sci B
January 2025
Department of Psychiatry, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Objectives: Whether vortioxetine has a utility as an adjuvant drug in the treatment of bipolar depression remains controversial. This study aimed to validate the efficacy and safety of vortioxetine in bipolar depression.
Methods: Patients with bipolar Ⅱ depression were enrolled in this prospective, two-center, randomized, 12-week pilot trial.
Biol Direct
January 2025
Department of Clinical Laboratory, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Hangzhou, Zhejiang, China.
Thioredoxin1 (TRX1) and telomerase are both attractive oncology targets that are tightly implicated in tumor initiation and development. Here, we reported that the 6-dithio-2-deoxyguanosine analog thiotert exhibits an effective cytotoxic effect on myelodysplastic syndromes (MDS) cell SKM-1 and lymphoma cell U-937. Further studies confirmed that thiotert effectively disrupts cellular redox homeostasis, as evidenced by elevated intracellular reactive oxygen species (ROS) levels, increased MnSOD, accelerated DNA impairment, and activated apoptosis signal.
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