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| http://dx.doi.org/10.3389/fgene.2022.983158 | DOI Listing |
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Comparative genome analysis of microbial strains marketed for probiotic interventions: an extension of the Integrated Probiotic Database.
Microbiome Res Rep
September 2024
Laboratory of Probiogenomics, Department of Chemistry, Life Sciences, and Environmental Sustainability University of Parma, Parma 43124, Italy.
Members of the genus and lactobacilli are the most commonly used probiotics to promote human health. In this context, genome-based analyses have been demonstrated as a fast and reliable tool for identifying and characterizing health-promoting activities imputed to probiotics. This study is an extension of the Integrated Probiotic Database (IPDB) previously created on probiotics of the genus , facilitating a comprehensive understanding of the genetic characteristics that contribute to the diverse spectrum of beneficial effects of probiotics.
View Article and Find Full Text PDFDistinct distribution and responses of IgM, IgT1 and IgT2 B cells in common carp.
Front Immunol
November 2024
Aquaculture and Fisheries Group, Department of Animal Sciences, Wageningen University & Research, Wageningen, Netherlands.
In teleosts, the immunoglobulin classes produced by B cells are IgM, IgD, and IgT/IgZ. IgT was initially described as an immunoglobulin specialized in mucosal responses; accumulating evidence, however, shows that it is also involved in systemic immune responses. Two types of IgT/IgZ (IgT1 and IgT2) were previously described in common carp, but their further characterization was hampered by the lack of specific tool.
View Article and Find Full Text PDFGut microbiota: a crucial player in the combat against tuberculosis.
Front Immunol
November 2024
Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Guangdong Medical University, Dongguan, Guangdong, China.
The mammalian gastrointestinal tract quickly becomes densely populated with foreign microorganisms shortly after birth, thereby establishing a lifelong presence of a microbial community. These commensal gut microbiota serve various functions, such as providing nutrients, processing ingested compounds, maintaining gut homeostasis, and shaping the intestinal structure in the host. Dysbiosis, which is characterized by an imbalance in the microbial community, is closely linked to numerous human ailments and has recently emerged as a key factor in health prognosis.
View Article and Find Full Text PDFWhole genome sequence analysis reveals high genomic diversity and potential host-driven adaptations among multidrug-resistant from pre-weaned dairy calves.
Front Microbiol
September 2024
Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States.
Article Synopsis
- Food-producing animals, like dairy cattle, can carry antimicrobial-resistant (AMR) bacteria, with young calves showing higher levels of multidrug-resistant (MDR) organisms compared to older cattle.
- The study focused on the genomes of MDR bacteria from pre-weaned dairy calves, finding that genomic diversity was primarily linked to specific sequence types and not heavily influenced by factors like diarrhea status or zinc supplementation.
- Despite lacking typical virulence factors, the MDR strains contained various virulence genes, particularly those involved in iron acquisition, suggesting that while host factors are not major drivers of genomic variability, certain accessory genes are enriched in these organisms.
Comparative analysis of energy homeostasis regulation at different altitudes in Hengduan Mountain of red-backed vole, , during high-fat diet acclimation: examining gut microbial and physiological interactions.
Front Microbiol
July 2024
Key Laboratory of Ecological Adaptive Evolution and Conservation on Animals-Plants in Southwest Mountain Ecosystem of Yunnan Province Higher Institutes College, School of Life Sciences, Yunnan Normal University, Kunming, China.
The study aimed to explore the similarities and differences in gut microorganisms and their functions in regulating body mass in across different altitudes in the Hengduan Mountains when exposed to a high-fat diet. specimens were gathered from Dali (DL) and Xianggelila (XGLL) in Yunnan Province, China, and categorized into control, high-fat (1 week of high-fat diet), and re-feeding groups (1 week of high-fat diet followed by 2 weeks of standard food). The analysis utilized 16S rRNA sequencing to assess the diversity and structure of intestinal microbial communities in .
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