Background/objectives: Watermelon rind (usually discarded by consumers) presents a high L-citrulline content. Given that Lcitrulline is involved in nitric oxide (NO) synthesis, a crucial molecule that regulates vascular function, this study aimed to evaluate the effect of microencapsulated watermelon rind (MWR) on endothelial function and tissue oxygen saturation (StO) assessed by flow-mediated dilation (FMD) and near-infrared spectroscopy, respectively. Plasma L-arginine and L-citrulline were also evaluated.
Subject/methods: Eleven participants ingested 30 g of MWR (containing 4 g of L-citrulline) and a placebo. Before and 30, 60, 90, and 120 min after ingestion, StO parameters were assessed, whereas FMD and plasma amino acids were analyzed 60 and 120 min after ingestion.
Results: The FMD improved 60 min after MWR without changes in StO parameters. Absolute plasma L-citrulline and relative change from baseline in plasma L-arginine increased 60 min after MWR ingestion.
Conclusion: A single dose of microencapsulated watermelon rind containing 4 g of L-citrulline seems adequate to improve FMD response, but not StO parameters in healthy adults. (NCT04781595).
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/s41430-022-01200-8 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Recent advances in probiotication of fruit and vegetable juices.
J Adv Vet Anim Res
September 2023
Department of Food Technology and Rural Industries, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Probiotics are live bacteria beneficial to health when consumed adequately. Health professionals now recommend probiotics on regular diets due to their positive effects on human health. The probiotics that are usually consumed from the market through food products are mostly dairy-based.
View Article and Find Full Text PDFDevelopment and characterization of a new potato starch/watermelon peel pectin composite film loaded with TiO nanoparticles and microencapsulated Lycium barbarum leaf flavonoids and its use in the Tan mutton packaging.
Int J Biol Macromol
December 2023
School of Food Science and Engineering, Ningxia University, Yinchuan, Ningxia 750021, China. Electronic address:
Reinforced edible film with active nanoparticles has been in increasing demand as a new technology to improve the quality and extend the shelf-life of muscle foods. The study aimed to fabricate and characterize a novel potato starch (Pst)/watermelon peel pectin (Wpp) composite film with the microencapsulated Lycium barbarum leaf flavonoids (MLF) and nano-TiO (Pst/Wpp/MLF/TiO) and further apply the film in Tan mutton preservation. The moisture content, thickness and water vapor permeability (WVP) of the composite film were relatively increased with increasing the percentage of MLF, while nano-TiO had slight influence on the thickness, but leaded to a significantly decreased the moisture content and WVP.
View Article and Find Full Text PDFThe effect of microencapsulated watermelon rind () and beetroot ( L.) ingestion on ischemia/reperfusion-induced endothelial dysfunction: a randomised clinical trial.
Food Funct
August 2023
Nutrition and Exercise Metabolism Research Group, Multidisciplinary Center UFRJ-Macaé, Federal University of Rio de Janeiro, Macaé, Rio de Janeiro, Brazil.
Endothelial dysfunction is commonly associated with a cardiovascular event, such as myocardial infarction. Myocardial infarction is marked by an ischemia/reperfusion (IR) phenomenon associated with endothelial dysfunction, contributing even more to future cardiovascular events. Although the supplementation with L-citrulline and nitrate from watermelon and beetroot have been used to improve vascular function, the effect of microencapsulated watermelon rind (WR) or its co-ingestion with beetroot (WR + B) on endothelial IR injury has not been addressed.
View Article and Find Full Text PDFEffect of microencapsulated watermelon (Citrullus Lanatus) rind on flow-mediated dilation and tissue oxygen saturation of young adults.
Eur J Clin Nutr
January 2023
Nutrition and Exercise Metabolism Research Group, Multidisciplinary Center UFRJ-Macaé, Federal University of Rio de Janeiro, Macaé, RJ, Brazil.
Background/objectives: Watermelon rind (usually discarded by consumers) presents a high L-citrulline content. Given that Lcitrulline is involved in nitric oxide (NO) synthesis, a crucial molecule that regulates vascular function, this study aimed to evaluate the effect of microencapsulated watermelon rind (MWR) on endothelial function and tissue oxygen saturation (StO) assessed by flow-mediated dilation (FMD) and near-infrared spectroscopy, respectively. Plasma L-arginine and L-citrulline were also evaluated.
View Article and Find Full Text PDFImpact of microencapsulated watermelon () and beetroot () on storage stability of l-citrulline and dietary nitrate.
J Food Sci Technol
December 2021
Nutrition and Exercise Metabolism Research Group, Nutrition Institute, Federal University of Rio de Janeiro, Macaé, Rio de Janeiro, Brazil.
The aim the current study was to developed a watermelon rind powder (WRP), watermelon pulp powder (WPP), and beetroot powder (BP), in order to compare the stability of L-citrulline and nitrate with that of watermelon rind juice (WRJ), watermelon pulp juice (WPJ), and beetroot juice (BJ), respectively. The stability was evaluated during 32 days at 25, 4 and - 20 ºC. L-arginine and L-ornithine content were also evaluated.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!