The Multidisciplinary drifting Observatory for the Study of Arctic Climate (MOSAiC) is a multinational interdisciplinary endeavor of a large earth system sciences community.
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| http://dx.doi.org/10.1038/s41597-022-01678-8 | DOI Listing |
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Comparison of Non-Invasive and Minimally Invasive Preimplantation Genetic Testing for Aneuploidy Using Samples Derived from the Same Embryo Culture.
J Clin Med
December 2024
Collegium Medicum, WSB University, 41-300 Dąbrowa Górnicza, Poland.
: To assess the ploidy status of embryos via preimplantation genetic testing for aneuploidy (PGT-A), a biopsy of trophectoderm (TE) cells can be performed. However, this approach is considered invasive, and therefore the aim of this study was to identify the optimal sample type and sampling day for non-invasive or minimally invasive PGT-A (ni/miPGT-A) in terms of data quality and concordance rates with TE biopsies derived from the same embryos. : This study was performed using 239 embryo cultures.
View Article and Find Full Text PDFRegeneration Filter: Enhancing Mosaic Algorithm for Near Salt & Pepper Noise Reduction.
Sensors (Basel)
January 2025
The Academy of Applied Technical and Preschool Studies, Aleksandra Medvedeva 20, 18000 Nis, Serbia.
This paper presents a Regeneration filter for reducing near Salt-and-Pepper (nS&P) noise in images, designed for selective noise removal while simultaneously preserving structural details. Unlike conventional methods, the proposed filter eliminates the need for median or other filters, focusing exclusively on restoring noise-affected pixels through localized contextual analysis in the immediate surroundings. Our approach employs an iterative processing method, where additional iterations do not degrade the image quality achieved after the first filtration, even with high noise densities up to 97% spatial distribution.
View Article and Find Full Text PDFCellular Partners of Tobamoviral Movement Proteins.
Int J Mol Sci
January 2025
Vavilov Institute of General Genetics Russian Academy of Sciences, 119333 Moscow, Russia.
The size of viral genomes is limited, thus the majority of encoded proteins possess multiple functions. The main function of tobamoviral movement protein (MP) is to perform plasmodesmata gating and mediate intercellular transport of the viral RNA. MP is a remarkable example of a protein that, in addition to the initially discovered and most obvious function, carries out numerous activities that are important both for the manifestation of its key function and for successful and productive infection in general.
View Article and Find Full Text PDFChromosomal Abnormalities in Miscarriages and Maternal Age: New Insights from the Study of 7118 Cases.
Cells
December 2024
D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Mendeleevskaya Line 3, 199034 Saint Petersburg, Russia.
Chromosomal abnormalities of the embryo are the most common cause of first-trimester pregnancy loss. In this single-center study, we assessed the frequency and the spectrum of chromosomal abnormalities in miscarriages for each year of maternal age from 23 to 44. Cytogenetic data were obtained by conventional karyotyping of 7118 miscarriages in women with naturally conceived pregnancies.
View Article and Find Full Text PDFDomain-Specific Prediction of Clinical Progression in Parkinson's Disease Using the Mosaic Approach.
Brain Behav
January 2025
Department of Neuroradiology, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Purpose: Due to the highly individualized clinical manifestation of Parkinson's disease (PD), personalized patient care may require domain-specific assessment of neurological disability. Evidence from magnetic resonance imaging (MRI) studies has proposed that heterogenous clinical manifestation corresponds to heterogeneous cortical disease burden, suggesting customized, high-resolution assessment of cortical pathology as a candidate biomarker for domain-specific assessment.
Method: Herein, we investigate the potential of the recently proposed Mosaic Approach (MAP), a normative framework for quantifying individual cortical disease burden with respect to a population-representative cohort, in predicting domain-specific clinical progression.
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