We report a rare case of polymicrobial anaerobic bacteremia caused by four different gut anaerobes: Bacteroides fragilis, Eggerthella lenta, Bilophila wadsworthia, and Ruminococcus gnavus. Early initiation of appropriate therapy and species identification with matrix assisted laser desorption time-of-flight mass spectrometry (MALDI-TOF MS) resulted in full recovery from the infection. Our case highlights the clinical significance of polymicrobial cultures and the importance of performing anaerobic cultures for blood specimens to ensure proper identification and treatment.
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http://dx.doi.org/10.1016/j.anaerobe.2022.102641 | DOI Listing |
J Infect Chemother
January 2025
Department of Clinical Laboratory, Kanazawa Medical University Hospital, 1-1 Daigaku, Uchinada, Kahoku, Ishikawa 920-0293, Japan; Department of Infectious Diseases, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Kahoku, Ishikawa, 920-0293, Japan. Electronic address:
A 70-year-old woman with a 6-month history of poor hygiene presented with a right occipital mass, ulceration, and neck swelling. The right occipital region was infested with approximately 100 fly maggots, and the mass contained a foul-smelling abscess. Maggots were removed, and the mass was drained, irrigated, and dressed with padding.
View Article and Find Full Text PDFNagoya J Med Sci
November 2024
Department of Clinical Infectious Diseases, Aichi Medical University, Nagakute, Japan.
() is known to cause intra-abdominal and anaerobic bloodstream infections. However, clinical insights and information on antimicrobial susceptibility in infections are limited. This study aimed to elucidate the clinical characteristics and antimicrobial susceptibility of infections.
View Article and Find Full Text PDFOtolaryngol Head Neck Surg
January 2025
Department of Surgery, Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida, USA.
Objective: Identify common pathogens and antibiotic resistances in chronic rhinosinusitis patients post-endoscopic sinus surgery presenting with an active sinus infection.
Study Design: Retrospective chart review.
Setting: Single-institution rhinology private practice in Southeast Florida.
ISME J
January 2025
Center for Fundamental and Applied Microbiomics, Biodesign Institue, Arizona State University, Tempe, AZ 85287.
The collective surface motility and swarming behavior of microbes play a crucial role in the formation of polymicrobial communities, shaping ecosystems as diverse as animal and human microbiota, plant rhizospheres, and various aquatic environments. In the human oral microbiota, T9SS-driven gliding bacteria transport non-motile microbes and bacteriophages as cargo, thereby influencing the spatial organization and structural complexity of these polymicrobial communities. However, the physical rules governing the dispersal of T9SS-driven bacterial swarms are barely understood.
View Article and Find Full Text PDFClin Oral Investig
December 2024
Department of Oral and Maxillofacial Plastic Surgery, University Medical Center of the University Bonn, Venusberg Campus 1, Building 11, 2. OG, D-53127, Bonn, Germany.
Objectives: This study aimed to map the microbiome of odontogenic abscesses using next-generation sequencing (NGS) to identify bacterial and fungal species, as well as antibiotic resistances.
Materials And Methods: Wound swabs were taken from patients treated for odontogenic abscesses at the Department of Oral and Maxillofacial Plastic Surgery, University Hospital Bonn. NGS was used to analyze the swabs, and bioinformatic analysis assigned the genetic material to microorganism profiles and identified antibiotic resistances.
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