A counterintuitive antibody cocktail disrupts coxsackievirus.

Cell Host Microbe

Department of Pediatrics, Division of Infectious Diseases, and Department of Microbiology & Immunology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA. Electronic address:

Published: September 2022

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Article Abstract

Utilizing monoclonal antibodies to prevent and treat infectious diseases has been accelerated by the COVID-19 pandemic. In this issue of Cell Host & Microbe, Zheng et al. show how a three-monoclonal-antibody cocktail, that defies conventions of "rational design" for a therapeutic agent, functions cooperatively to disrupt coxsackievirus virions.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9472682PMC
http://dx.doi.org/10.1016/j.chom.2022.08.010DOI Listing

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