For most technologies, the cure is likely worse than the disease.
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http://dx.doi.org/10.1126/science.abq5446 | DOI Listing |
Neurol Sci
January 2025
Epilepsy Center, Department of Neurology, West China Hospital of Sichuan University, Chengdu, China.
This study intents to detect graphical network features associated with seizure relapse following antiseizure medication (ASM) withdrawal. Twenty-four patients remaining seizure-free (SF-group) and 22 experiencing seizure relapse (SR-group) following ASM withdrawal as well as 46 matched healthy participants (Control) were included. Individualized morphological similarity network was constructed using T1-weighted images, and graphic metrics were compared between groups.
View Article and Find Full Text PDFEnviron Sci Technol
January 2025
School of Engineering, Hangzhou Normal University, Hangzhou 310018, China.
Bacterial denitrification is a main pathway for soil NO sinks, which is crucial for assessing and controlling NO emissions. Biobased polyhydroxyalkanoate (PHA) microplastic particles (MPs) degrade slowly in conventional environments, remaining inert for extended periods. However, the impacts of PHA microplastic aging on the bacterial NO sink capacity before degradation remain poorly understood.
View Article and Find Full Text PDFJ Psychiatry Neurosci
January 2025
From the Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China (Gong, Wang, Nie, Ma, Zhou, Deng, Xie, Lyu, Chen, Kang, Liu); the Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China (Liu)
Background: Cortical morphometry is an intermediate phenotype that is closely related to the genetics and onset of major depressive disorder (MDD), and cortical morphometric networks are considered more relevant to disease mechanisms than brain regions. We sought to investigate changes in cortical morphometric networks in MDD and their relationship with genetic risk in healthy controls.
Methods: We recruited healthy controls and patients with MDD of Han Chinese descent.
Sci Rep
December 2024
Department of Ecology and Evolutionary Biology, Cornell University, Ithaca, NY, USA.
Consumers vary in their excretion of nitrogen and phosphorus, altering nutrient cycles and ecosystem function. Traditional mass balance models that focus on dietary and tissue nutrients have poorly explained such variation in excretion. Here, we contrast diet and tissue nutrient models for nutrient excretion with predation risk, an often overlooked factor, using the Trinidadian guppy (Poecilia reticulata) as our model system.
View Article and Find Full Text PDFJ Thromb Haemost
December 2024
Division of Cardiovascular Medicine, Department of Internal Medicine, Frankel Cardiovascular Center, University of Michigan, Ann Arbor, Michigan, USA. Electronic address:
Arterial and venous thromboses are the leading causes of morbidity and mortality worldwide. Numerous antithrombotic agents are currently available with antiplatelet, thrombolytic/fibrinolytic, and anticoagulant activity. However, all the currently available antithrombotic agents carry a risk of bleeding that often prevents their use.
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