AI Article Synopsis
- The study aimed to compare the outcomes of total glossectomy with laryngeal preservation (TGLP) to near-total glossectomy with laryngeal preservation (nTGLP) in patients with advanced tongue cancer.
- It analyzed data from 23 patients who underwent either surgical procedure over a ten-year period, focusing on factors like survival rates and necessity for tracheostomy or gastric tube dependence.
- The findings suggested that both surgical options are viable with similar functional and oncological outcomes, but overall survival and recurrence rates were not satisfactory, emphasizing the need for careful patient selection for long-term rehabilitation.
Article Abstract
Objective: The purpose of this study was to evaluate the functional and oncological outcomes of total glossectomy with laryngeal preservation (TGLP) compared to near-total glossectomy with laryngeal preservation (nTGLP).
Methods: In this retrospective study, the data of 23 patients who underwent either TGLP or nTGLP between January 2010 and December 2020 in a tertiary university hospital were analyzed. The data including demographic findings, tumor stage, extent of surgery and technique, method of reconstruction, complications, overall survival (OS) and recurrence-free survival (RFS), and tracheostomy and gastric tube dependence during follow-up were assessed.
Results: Of the 23 eligible patients, 15 had undergone nTGLP (Group 1) and 8 had undergone TGLP (Group 2). Tracheostomy dependence and gastric tube dependence rates at the sixth month were 3/19 (15.7%) and 12/19 (63.1%), respectively, with no significant differences between the two groups. OS and RFS at one year were 47.6% and 27.8%, respectively, for the study population. OS rate showed significance with nodal positivity and extranodal extension (p=0.004 for both) only, but not within patient groups (p=0.734).
Conclusion: Both TGLP and nTGLP are feasible treatment options in patients with advanced tongue cancer with no differences in terms of functional and oncological results. Survival rates are still not satisfactory, and recurrences are high despite appropriate treatments. Proper selection of patients who are highly motivated and willing for long-term postoperative rehabilitation is essential.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435387 | PMC |
| http://dx.doi.org/10.4274/tao.2022.2022-4-1 | DOI Listing |
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