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Predictive signatures of immune response to vaccination and implications of the immune setpoint remodeling.
mSphere
January 2025
Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
In 2020, I featured two articles in the "mSphere of Influence" commentary series that had profound implications for the field of immunology and helped shape my research perspective. These articles were "Global Analyses of Human Immune Variation Reveal Baseline Predictors of Postvaccination Responses" by Tsang et al. (Cell 157:499-513, 2014, https://doi.
View Article and Find Full Text PDFInterplay between creeping fat and gut microbiota: A brand-new perspective on fecal microbiota transplantation in Crohn's disease.
World J Gastroenterol
January 2025
Department of Gastroenterology, The First Affiliated Hospital of University of Science and Technology of China, Hefei 230001, Anhui Province, China.
Inflammatory bowel disease, particularly Crohn's disease (CD), has been linked to modifications in mesenteric adipose tissue (MAT) and the phenomenon known as "creeping fat" (CrF). The presence of CrF is believed to serve as a predictor for early clinical recurrence following surgical intervention in patients with CD. Notably, the incorporation of the mesentery during ileocolic resection for CD has been correlated with a decrease in surgical recurrence, indicating the significant role of MAT in the pathogenesis of CD.
View Article and Find Full Text PDFReply: Unveiling early predictors of adverse birth outcomes: the potential and limits of embryonic growth metrics.
Hum Reprod
January 2025
Division of Neonatology, Department of Neonatal and Pediatric Intensive Care, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.
The Predictive Significance of Platelet-to-Lymphocyte Ratio for Miscarriage: A Systematic Review and Meta-Analysis.
Immun Inflamm Dis
January 2025
Obstetrics Department, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
Background: Miscarriage is a common complication of pregnancy, and its underlying pathophysiologic mechanisms remains unclear. The platelet-to-lymphocyte ratio (PLR), a prothrombotic and inflammatory marker, has been controversially discussed as a potential predictor of miscarriage. This systematic review and meta-analysis aimed to assess the predictive significance of the PLR in women with miscarriage compared to healthy pregnancies.
View Article and Find Full Text PDFCommentary on "Frailty as a predictor of mortality in the oldest old: A systematic review and meta-analysis".
Geriatr Gerontol Int
January 2025
Department of Paediatrics, Dr. D. Y. Patil Medical College Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed-to-be-University), Pune, India.
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