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Computational Neurosurgery in Deep Brain Stimulation.
Adv Exp Med Biol
November 2024
Division of Neurosurgery, Department of Surgery, University Health Network, University of Toronto, Toronto, ON, Canada.
Computational methods and technologies are critical for neurosurgery in general and in deep brain stimulation (DBS) in particular. They increasingly inform every aspect of clinical DBS therapy, from presurgical planning and hardware implantation to postoperative adjustment of stimulation parameters. Computational methods also occupy a prominent position within the DBS research sphere, where they facilitate efforts to better understand DBS' underlying mechanisms and optimize and individualize its delivery.
View Article and Find Full Text PDFColor, pattern, and background contrast affect attraction of Euxesta eluta and Chaetopsis massyla (Diptera: Ulidiidae).
Environ Entomol
February 2024
United States Department of Agriculture, Agricultural Research Service, Center for Medical, Agricultural and Veterinary Entomology, Gainesville, FL, USA.
Euxesta eluta Loew and Chaetopsis massyla Walker (Diptera: Ulidiidae) are primary pests of sweet corn in Florida. Attraction of adult flies to various visual stimuli was evaluated in the laboratory to provide insight into the potential development of enhanced trapping strategies. In assays evaluating different colored sticky traps, more E.
View Article and Find Full Text PDFFluid Optimisation in Emergency Laparotomy (FLO-ELA) Trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery.
Trials
May 2023
Perioperative & Critical Care Research Group, NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust / University of Southampton, Southampton, UK.
Article Synopsis
- * The FLO-ELA trial is described as a large-scale study involving over 3,100 patients aged 50 and older, comparing heart-monitoring guided fluid management to standard care.
- * The main goal of the trial is to measure how many days patients are alive and out of the hospital within 90 days post-surgery, and it aims to provide evidence to improve clinical practices in emergency surgical settings.
Interface Manipulations Using Cross-Linked Underlayers and Surface-Active Diblock Copolymers to Extend Morphological Diversity in High-χ Diblock Copolymer Thin Films.
ACS Appl Mater Interfaces
May 2023
Univ Grenoble Alpes, CNRS, CERMAV, F-38000 Grenoble, France.
Top and bottom interfaces of high-χ cylinder-forming polystyrene--maltoheptaose (PSMH) diblock copolymer (BCP) thin films are manipulated using cross-linked copolymer underlayers and a fluorinated phase-preferential surface-active polymer (SAP) additive to direct the self-assembly (both morphology and orientation) of BCP microdomains into sub-10 nm patterns. A series of four photo-cross-linkable statistical copolymers with various contents of styrene, a 4-vinylbenzyl azide cross-linker, and a carbohydrate-based acrylamide are processed into 15 nm-thick cross-linked passivation layers on silicon substrates. A partially fluorinated analogue of the PSMH phase-preferential SAP additive is designed to tune the surface energy of the top interface.
View Article and Find Full Text PDFDevelopment of an x-ray radiography platform to study laser-direct-drive energy coupling at the National Ignition Facility.
Rev Sci Instrum
October 2022
Laboratory for Laser Energetics, University of Rochester, Rochester, New York 14623-1299, USA.
A platform has been developed to study laser-direct-drive energy coupling at the National Ignition Facility (NIF) using a plastic sphere target irradiated in a polar-direct-drive geometry to launch a spherically converging shock wave. To diagnose this system evolution, eight NIF laser beams are directed onto a curved Cu foil to generate He line emission at a photon energy of 8.4 keV.
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