Background: Pharyngitis is a common presentation seen in general practice, but it is difficult to differentiate whether its etiology is viral or bacterial. The Centor score gives an approximation of the etiology of the pharyngitis, which informs physicians of the need to prescribe antibiotics. This study aimed to assess the validity of the Centor score in diagnosing Group A streptococcal (GAS) pharyngitis amongst adults in Malaysia.

Methods: This cross-sectional study was conducted to compare the clinical criteria of the Centor score to the gold standard throat swab culture results amongst 215 adults presenting with sore throat in primary care clinics. The participants were adult patients who complained of sore throat and visited the three public primary care clinics in Sepang, Malaysia. The convenience sampling method was used. The throat swabs were analysed for β-haemolytic streptococci. Demographic and clinical data, including the Centor score, were analysed in relation to the pathogen.

Results: Pharyngitis was diagnosed in 130 (60.5%) of the participants. Six isolates (2.4%) were identified as GAS pharyngitis. Both Centor scores 3 and 4 had a sensitivity of 50%, and specificities of 97.6% and 100%, respectively.

Conclusion: A Centor score < 3 is favourable for excluding a diagnosis of GAS pharyngitis. Centor scores 3 and 4 require further examination to confirm a diagnosis of GAS pharyngitis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438850PMC
http://dx.doi.org/10.21315/mjms2022.29.4.9DOI Listing

Publication Analysis

Top Keywords

centor score
24
gas pharyngitis
16
primary care
12
care clinics
12
centor
8
group streptococcal
8
pharyngitis
8
pharyngitis adults
8
sore throat
8
pharyngitis centor
8

Similar Publications

The diagnosis of streptococcal throat infection is an area where current practice results in significant over-diagnosis of bacterial infection, with the resulting implications for antimicrobial use and resistance. The use of molecular point of care testing (POCT) has previously been shown to alter antibiotic prescribing decisions when compared to Centor scoring. This paper explores the impact of the addition of POCT to clinical assessment using the McIsaac and FeverPAIN scoring systems.

View Article and Find Full Text PDF

Inter-rater reliability of Centor score assessments between telemedicine and in-person examinations in patients with an acute sore throat.

Infect Dis (Lond)

November 2024

General Practice/Family Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Article Synopsis
  • - The study investigates the reliability of Centor score assessments for sore throats during telemedicine visits compared to in-person evaluations to see if these methods yield consistent results.
  • - Each patient underwent a telemedicine assessment followed by a blind in-person assessment, and the agreement between both methods was measured using Cohen's kappa coefficient, revealing a low reliability overall.
  • - Results showed that telemedicine assessments are not reliable for determining Centor criteria in sore throat cases, with little difference in reliability between children and adults.
View Article and Find Full Text PDF

Centor scores associated poorly with rapid antigen test findings in children with sore throat.

Eur J Pediatr

November 2024

Institute of Clinical Medicine and Department of Pediatrics, University of Eastern Finland, Yliopistonranta 2, 70211, Kuopio, Finland.

Unlabelled: The Finnish Current Care Guideline recommends rapid antigen tests as the primary diagnostic tool for both adults and children with Centor score ≥ 3. We aimed to analyze the association of Centor score and rapid antigen test positivity of group A streptococcal pharyngitis (GAS) in Finnish children. We performed a retrospective single-center study from July 2019 to June 2022.

View Article and Find Full Text PDF
Article Synopsis
  • * The research included 60 children aged 2-17 with sore throats and high fevers, categorizing them into groups based on their diagnosis.
  • * Although IRT alone couldn't differentiate between bacterial and viral pharyngitis, it improved the prediction accuracy for streptococcal pharyngitis when used with the McIsaac score, achieving a 90% positive predictive value.
View Article and Find Full Text PDF

Background: This work was undertaken to inform a National Institute for Health and Care Excellence guideline on the initial assessment of adults with suspected acute respiratory infection.

Objective: To undertake a rapid evidence synthesis of systematic reviews and cost-effectiveness studies of signs, symptoms and early warning scores for the initial assessment of adults with suspected acute respiratory infection.

Methods: MEDLINE, EMBASE and Cochrane Database of Systematic Reviews were searched for systematic reviews and MEDLINE, EMBASE, EconLit and National Health Service Economic Evaluation Database were searched for cost-effectiveness studies in May 2023.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!