Preparation of a novel group of chemiluminescent N-substituted acridinium esters.

Luminescence

Cornea Research Chair, Department of Optometry, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.

Published: November 2022

AI Article Synopsis

  • Researchers synthesized new N-substituted acridinium esters (7-16) with different 10-position alkyl groups, including 10-methyl and 10-dodecyl.
  • The study measured the chemiluminescent properties, revealing that the efficiency and stability of these compounds depend on the specific group attached to the nitrogen atom.
  • It was found that dibromo-substituted leaving groups can slightly enhance the speed of the chemiluminescence reaction.

Article Abstract

Several novel N-substituted acridinium esters 7-16 containing a 10-methyl, 10-dodecyl, or 10-(ω-[succinimidyloxycarbonyl]alkyl) group have been synthesized and their chemiluminescent properties have been tested. Their chemiluminescent efficiencies and hydrolytic stabilities have been found to be affected by the characteristics of the group on the nitrogen atom. Dibromo-substituted leaving groups slightly accelerate the chemiluminescence process.

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Source
http://dx.doi.org/10.1002/bio.4385DOI Listing

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