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Foreign Contaminants Target Brain Health.
CNS Neurol Disord Drug Targets
January 2025
Department of Pharmaceutical Chemistry, Delhi Pharmaceutical Sciences & Research University, Delhi, India-110017.
Neurodisease, caused by undesired substances, can lead to mental health conditions like depression, anxiety and neurocognitive problems like dementia. These substances can be referred to as contaminants that can cause damage, corruption, and infection or reduce brain functionality. Contaminants, whether conceptual or physical, have the ability to disrupt many processes.
View Article and Find Full Text PDF[Introduction of the Low and Medium Security Psychiatry Unit at the Nyírô Gyula National Institute of Psychiatry and Addictology].
Psychiatr Hung
January 2025
Országos Pszichiátriai és Addiktológiai Intézet, Budapest, Hungary, E-mail:
Under the direction of the National Directorate General for Hospitals, and based on British examples and methodology, a new inpatient psychiatric ward with a high security level started operating at the National Institute of Psychiatry and Addictology in October 2023. As a new, independent unit, the High Security Psychiatry is a niche in Hungarian psychiatric care. The aim of the project was to reduce the burden on the whole mental health care system in Hungary, to increase public confidence in care and the safety of society through organizing of a specialised care team operating in an appropriate infrastructural environment.
View Article and Find Full Text PDFPrediction of Potential Risk for Ten Azole and Benzimidazole Fungicides with the Aryl Hydrocarbon Receptor Agonistic Activity to Aquatic Ecosystems.
J Agric Food Chem
January 2025
Fujian Engineering Research Center for Green Pest Management/Fujian Key Laboratory for Monitoring and Integrated Management of Crop Pests/East China Branch of the National Center for Agricultural Biosafety Sciences, Institute of Plant Protection, Fujian Academy of Agricultural Sciences, Fuzhou 350013, China.
Azole and benzimidazole fungicides are widely used agrochemicals to prevent and treat fungal growth and are frequently detected in aquatic environments. Here, we aimed to assess the aquatic ecological risks of ten currently used azole and benzimidazole fungicides, which with the aryl hydrocarbon receptor (AhR) agonistic activity, and their transformation products (TPs). We obtained over 400 types of aerobic TPs for ten fungicides.
View Article and Find Full Text PDFSafety Assessment of Graphene-Based Materials.
Small
January 2025
Center for Cooperative Research in Biomaterials (CIC biomaGUNE), Basque Research and Technology Alliance (BRTA), San Sebastián, 20014, Spain.
Graphene is the first 2D atomic crystal, and its isolation heralded a new era in materials science with the emergence of several other atomically thin materials displaying multifunctional properties. The safety assessment of new materials is often something of an afterthought, but in the case of graphene, the initial isolation and characterization of the material was soon followed by the assessment of its potential impact on living systems. The Graphene Flagship project addressed the health and environmental aspects of graphene and other 2D materials, providing an instructive lesson in interdisciplinarity - from materials science to biology.
View Article and Find Full Text PDFUnveiling the toxicity of micro-nanoplastics: A systematic exploration of understanding environmental and health implications.
Toxicol Rep
June 2025
Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur 56000, Malaysia.
The surge in plastic production has spurred a global crisis as plastic pollution intensifies, with microplastics and nanoplastics emerging as notable environmental threats. Due to their miniature size, these particles are ubiquitous across ecosystems and pose severe hazards as they are ingested and bioaccumulate within organisms. Although global plastic production has reached an alarming 400.
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