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[Improving Specialist Care for Patients in Out-of-Hospital Intensive Care through Regular Pulmonological Video Consultations: A Real-life Study].
Pneumologie
January 2025
Veritas Videoconsult GmbH, Herford, Deutschland.
Background: In recent years, there has been a significant increase in the number of patients requiring out-of-hospital intensive care. Although many of these patients are invasively ventilated, pulmonological care is often lacking. Additionally, up to 60-70% of these patients are suspected to have further potential for weaning.
View Article and Find Full Text PDFPortal venous gas value in predicting surgical necrotizing enterocolitis.
Pediatr Res
January 2025
Division of Pediatric Surgery, Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
This commentary highlights the study by Yixian et al., "Value of portal venous gas and a nomogram for predicting severe neonatal necrotizing enterocolitis.".
View Article and Find Full Text PDFComputational exploration of injection strategies for improving medicine distribution in the liver.
Comput Biol Med
December 2024
Faculty of Chemical & Petroleum Engineering, University of Tabriz, Tabriz, Iran. Electronic address:
Background And Objectives: The liver, a vital metabolic organ, is always susceptible to various diseases that ultimately lead to fibrosis, cirrhosis, acute liver failure, chronic liver failure, and even cancer. Optimal and specific medicine delivery in various diseases, hepatectomy, shunt placement, and other surgical interventions to reduce liver damage, transplantation, optimal preservation, and revival of the donated organ all rely on a complete understanding of perfusion and mass transfer in the liver. This study aims to simulate the computational fluid dynamics of perfusion and the temporal-spatial distribution of a medicine in a healthy liver to evaluate the hemodynamic characteristics of flow and medicine transport with the purpose of more effective liver treatment.
View Article and Find Full Text PDFMetabolomic Changes Associated With the Change in HVPG After DAAs Therapy in HCV Cirrhotic Patients.
Liver Int
January 2025
Unidad de Infección Viral e Inmunidad, Centro Nacional de Microbiología (CNM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
Background And Aims: In response to direct-acting antivirals (DAAs) therapy, patients who experience a decrease in hepatic venous pressure gradient (HVPG) considerably reduce liver complications and have increased survival. This study aimed to assess the metabolomic changes associated with the changes in HVPG from the start of DAA therapy until 48 weeks after effective DAA therapy in patients with advanced HCV-related cirrhosis.
Methods: We carried out a multicenter longitudinal study in 31 patients with advanced hepatitis C virus (HCV)-related cirrhosis.
Controlled low central venous pressure maintenance level during laparoscopic hepatectomy negatively associated with PHLF incidence: a retrospective propensity score matching study.
Surg Endosc
December 2024
Department of Anesthesiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, People's Republic of China.
Background: Posthepatectomy liver failure (PHLF), the most serious complication after hepatectomy, may evoke multisystemic complications and even mortality. Despite numerous studies demonstrated the safety and efficacy of controlled low central venous pressure (CLCVP), the optimal central venous pressure (CVP) maintenance level during CLCVP and its relationship with PHLF remain controversial. Therefore, the present study aimed to evaluate the association between the lowest CVP maintenance level during CLCVP and PHLF.
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