Study on the Effect of a Mixture of Extract and Panax Ginseng on Testosterone Content and Semen Quality in Experimental Rats.

<b>Background and Objective:</b> <i>Hippocampus kuda</i> and ginseng are commonly known for male sexual function mainly for their potency and libido enhancement effects, however, no study was reported that incorporates these fluids. This study aimed at the extraction of these two ingredients to understand the synergistic effect of increasing testosterone content and semen quality was studied in this article. <b>Materials and Methods:</b> After extracting and creating extracts of <i>Hippocampus kuda</i> and ginseng, a 1:1 extract was mixed to create a mixture of both ingredients. <b>Results:</b> The results obtained from this study confirmed that alcohol extracts from <i>Hippocampus kuda</i> and Panax ginseng have a positive effect on testosterone content and semen quality. In particular, the combination of extracts from these two ingredients significantly improves testosterone content and semen quality compared with using extracts separately. <b>Conclusion:</b> High-extract mixture extracted by alcohol from <i>Hippocampus kuda</i> and Panax ginseng at the rate of 1/1 showed a superior effect in increasing testosterone content and semen quality compared to the extract of each material. A high extract mixture used at a dosage of 240 mg/100 g body weight/day is suitable for increasing the testosterone content, increasing sperm density, increasing the survival rate of spermatozoa and reducing the rate of malformed sperm in real rats experience.