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Nine years of patch testing with isocyanates in a clinic of occupational dermatology.
Contact Dermatitis
September 2024
Occupational Medicine, Finnish Institute of Occupational Health (FIOH), Helsinki, Finland.
Background: Isocyanates are used as starting materials of polyurethane (PU) products. They are relatively important occupational skin sensitizers.
Objectives: To analyse results of a large isocyanate patch test series of 19 isocyanate test substances and 4,4'-diaminodiphenylmethane (MDA), a marker of 4,4'-diphenylmethane diisocyanate (MDI) hypersensitivity.
Environmental and occupational exposure to bisphenol compounds in Finland.
Toxicol Lett
July 2024
Finnish Institute of Occupational Health, PO Box 40, Työterveyslaitos FI-00032, Finland.
The aim of the study was to assess non-occupational and occupational exposure to bisphenol compounds in Finland. The participants were 151 non-occupationally exposed volunteers and 15 potentially exposed employees of a sewage-pipe relining company and a floor-coating company. The following chemicals were measured in the urine samples: bisphenol A (BPA), bisphenol F (BPF), bisphenol A diglycidyl ether (BADGE), bisphenol F diglycidyl ether (BFDGE), and the metabolites of the latter two [bisphenol A (2,3-dihydroxypropyl) glycidyl ether (BADGE·HO), bisphenol A bis(2,3-dihydroxypropyl) ether (BADGE·2 HO), bisphenol A (3-chloro-2-hydroxypropyl) (2,3-dihydroxypropyl) ether (BADGE·HCl·HO), bisphenol A (3-chloro-2-hydroxypropyl) glycidyl ether (BADGE·HCl), and bisphenol A bis(3-chloro-2-hydroxypropyl) ether (BADGE·2HCl) and bisphenol F bis(2,3-dihydroxypropyl) ether (BFDGE·2 HO), and bisphenol F bis(3-chloro-2-hydroxypropyl) ether (BFDGE·2HCl)].
View Article and Find Full Text PDFPipe relining: Not only epoxy resins. Two cases of occupational contact allergy to acrylates.
Contact Dermatitis
January 2023
Department of Occupational and Environmental Dermatology, Lund University, Skåne University Hospital, Malmö, Sweden.
Characterization of patients with occupational allergy to two new epoxy hardener compounds.
Contact Dermatitis
July 2022
Occupational Medicine, Finnish Institute of Occupational Health (FIOH), Helsinki, Finland.
Article Synopsis
- Two newly identified epoxy hardener allergens, 1,3-BDMA-D and FBAP, are being studied for their significance as occupational allergens.
- A study at the Finnish Institute of Occupational Health revealed that 19 out of 102 patients tested positive for allergies related to these substances, notably affecting workers in occupations like sewage pipe relining.
- The research highlights the need for awareness about these allergens, with a majority of cases linked to specific hardener products.
Skin exposure to epoxy chemicals in construction coating, assessed by observation, interviews, and measurements.
Contact Dermatitis
January 2019
Solutions for Safety, Finnish Institute of Occupational Health, Helsinki, Finland.
Background: Epoxy resin systems (ERSs) are among the leading causes of occupational allergic contact dermatitis.
Objectives: To identify riskful exposures and sources of skin exposure, and to quantify skin exposure to diglycidyl ether of bisphenol A (DGEBA) epoxy monomer, in construction coating work.
Methods: Skin exposure to epoxy chemicals was studied in 5 coating companies through (a) interviews and visual observation, (b) quantifying DGEBA on 12 workers' skin by tape-stripping, (c) measuring DGEBA on 23 surfaces by wipe-sampling, and (d) quantifying DGEBA in new sewage pipe.
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