Gold nanoparticles: current and upcoming biomedical applications in sensing, drug, and gene delivery.

Chem Commun (Camb)

Laboratorio de Fisicoquímica y Reactividad de Superficies (LaFReS), Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de Mexico, Circuito Exterior S/N, CU, Del. Coyoacán, Ciudad de Mexico, 04510, Mexico.

Published: September 2022

AI Article Synopsis

  • * A major challenge in using AuNPs is enhancing their sensitivity and selectivity for better sensing methods and multifunctional platforms for drug or gene delivery.
  • * The review focuses on recent advancements in AuNPs within the field of biomedicine, emphasizing their roles as biosensors and targeted delivery systems.

Article Abstract

Gold nanoparticles (AuNPs) present unique physicochemical characteristics, low cytotoxicity, chemical stability, size/morphology tunability, surface functionalization capability, and optical properties which can be exploited for detection applications (colorimetry, surface-enhanced Raman scattering, and photoluminescence). The current challenge for AuNPs is incorporating these properties in developing more sensible and selective sensing methods and multifunctional platforms capable of controlled and precise drug or gene delivery. This review briefly highlights the recent progress of AuNPs in biomedicine as bio-sensors and targeted nano vehicles.

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Source
http://dx.doi.org/10.1039/d2cc04826dDOI Listing

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