Cardiovascular disease (CVD) has long been deemed a disease of old men. However, in 2019 CVD accounted for 35% of all deaths in women and, therefore, remains the leading cause of death in both men and women. There is increasing evidence to show that risk factors, pathophysiology and health outcomes related to CVD differ in women compared with men, yet CVD in women remains understudied, underdiagnosed and undertreated. Differences exist between the sexes in relation to the structure of the heart and vasculature, which translate into differences in blood pressure and flow waveform physiology. These physiological differences between women and men may represent an important explanatory factor contributing to the sex disparity in CVD presentation and outcomes but remain understudied. In this review we aim to describe sex differences in arterial pressure and flow waveform physiology and explore how they may contribute to differences in CVD in women compared to men. Given that unfavourable alterations in the cardiovascular structure and function can start as early as in utero, we report sex differences in waveform physiology across the entire life course.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/HJH.0000000000003283 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Optimizing Mechanical Ventilation: A Clinical and Practical Bedside Method for the Identification and Management of Patient-Ventilator Asynchronies in Critical Care.
J Clin Med
January 2025
Department of Critical Care Medicine, Hospital de São Francisco Xavier, Unidade Local de Saúde Lisboa Ocidental (ULSLO), Estrada Forte do Alto Duque, 1449-005 Lisbon, Portugal.
The prompt identification and correction of patient-ventilator asynchronies (PVA) remain a cornerstone for ensuring the quality of respiratory failure treatment and the prevention of further injury to critically ill patients. These disruptions, whether due to over- or under-assistance, have a profound clinical impact not only on the respiratory mechanics and the mortality associated with mechanical ventilation but also on the patient's cardiac output and hemodynamic profile. Strong evidence has demonstrated that these frequently occurring and often underdiagnosed events have significant prognostic value for mechanical ventilation outcomes and are strongly associated with prolonged ICU stays and hospital mortality.
View Article and Find Full Text PDFDHCT-GAN: Improving EEG Signal Quality with a Dual-Branch Hybrid CNN-Transformer Network.
Sensors (Basel)
January 2025
Guangdong Institute of Intelligence Science and Technology, Hengqin, Zhuhai 519031, China.
Electroencephalogram (EEG) signals are important bioelectrical signals widely used in brain activity studies, cognitive mechanism research, and the diagnosis and treatment of neurological disorders. However, EEG signals are often influenced by various physiological artifacts, which can significantly affect data analysis and diagnosis. Recently, deep learning-based EEG denoising methods have exhibited unique advantages over traditional methods.
View Article and Find Full Text PDFSmart furniture using radar technology for cardiac health monitoring.
Sci Rep
January 2025
Department of Electrical and Computer Engineering, University of Waterloo, Waterloo, ON, Canada.
The integration of radar technology into smart furniture represents a practical approach to health monitoring, circumventing the concerns regarding user convenience and privacy often encountered by conventional smart home systems. Radar technology's inherent non-contact methodology, privacy-preserving features, adaptability to diverse environmental conditions, and high precision characteristics collectively establish it a compelling alternative for comprehensive health monitoring within domestic environments. In this paper, we introduce a millimeter (mm)-wave radar system positioned strategically behind a seat, featuring an algorithm capable of identifying unique cardiac waveform patterns for healthy subjects.
View Article and Find Full Text PDFElectric field stimulation directs target-specific axon regeneration and partial restoration of vision after optic nerve crush injury.
PLoS One
January 2025
Department of Ophthalmology, Keck School of Medicine, USC Roski Eye Institute, University of Southern California, Los Angeles, California, United States of America.
Failure of central nervous system (CNS) axons to regenerate after injury results in permanent disability. Several molecular neuro-protective and neuro-regenerative strategies have been proposed as potential treatments but do not provide the directional cues needed to direct target-specific axon regeneration. Here, we demonstrate that applying an external guidance cue in the form of electric field stimulation to adult rats after optic nerve crush injury was effective at directing long-distance, target-specific retinal ganglion cell (RGC) axon regeneration to native targets in the diencephalon.
View Article and Find Full Text PDFA Double-Blind Comparative Study of burstDR Versus Tonic Epidural Motor Cortex Stimulation for the Treatment of Intractable Neuropathic Pain.
Eur J Pain
February 2025
Department of Neurosurgery, University Hospital of Saint-Etienne, Saint-Priest-en-Jarez, France.
Background: Preliminary studies on epidural motor cortex stimulation (eMCS) for the treatment of drug-resistant neuropathic pain have supported the extension to novel stimulation waveforms, in particular burstDR. However, only a low level of evidence is available. The aim of this retrospective observational study was to compare the analgesic efficacy of burstDR versus tonic eMCS.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!