A new twist for Stork-Danheiser products enabled by visible light mediated -cyclohexene formation; access to acyclic distal enones.

Herein, we investigate the use of visible light to indirectly drive ring opening in unstrained 6- and 7-membered ring systems reaction with a transiently generated -cycloalkene. Identification of conditions that capture visible light energy in the form of ring strain was key to success. Under mildly acidic conditions, cycloalkenols were shown to undergo formally endothermic ring-opening isomerization to give acyclic exo-methylene and distal ketones or aldehydes in high yields. Ultimately, this work demonstrates the ability of cycloalkenes to capture visible light energy and its use to drive both kinetically and thermally unfavorable rearrangements.