AI Article Synopsis
- The study investigates key virulence factors like adhesion to host cells, hemolysin production, and proteinase activity in relation to infections caused by certain isolates from gastroesophageal lesions and urinary tract infections.
- 97 isolates were tested for their ability to adhere to cells, produce proteinases, and hemolysins, with statistical methods applied to analyze the data.
- Findings indicate that while all isolates demonstrated proteinase activity, there was no significant difference in adhesion or hemolytic activity between the groups, suggesting that the pathogenicity of these isolates does not directly relate to the infected site.
Article Abstract
Background: Adhesion of to host cell receptors, hemolysin production, and proteinase activity are assumed as principal virulence factors and infection establishment. These virulence factors are essential for colonization, biofilm formation, and attack on the host cells.
Materials And Methods: A total of 97 isolates obtained from gastroesophageal lesions and urinary tract infections were included in the study. Adhesion assay, proteinase activity, and hemolysin production were measured. Statistical analysis was performed using the independent -test and Chi-square test to compare quantitative and qualitative data between the two groups.
Results: The adherence ability to the buccal epithelial cells was the same in the two groups. Proteinase activity was seen in all clinical isolates. Hemolytic activities were not statistically significant in the two groups.
Conclusion: Our results recommend that the pathogenicity of in the mucous membranes cannot be connected to the infected site.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9450245 | PMC |
| http://dx.doi.org/10.4103/jrms.jrms_35_22 | DOI Listing |
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