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http://dx.doi.org/10.4103/ijd.ijd_617_21 | DOI Listing |
Diagnostics (Basel)
December 2024
UOC of Dermatology, Policlinico Umberto I Hospital, Sapienza Medical School of Rome, 00161 Rome, Italy.
Early detection and comprehensive diagnostic approaches for breast cancer are essential for improving prognosis. When it comes to changes in the skin of the breast or the nipple-areola complex (NAC), particularly if they are unilateral, it is essential to be vigilant, as these changes could be an early sign of underlying malignancy or other pathologies. Primary breast malignancies, such as mammary Paget's disease (MPD), can manifest as erythema, scaling, or ulceration of the NAC, while secondary cutaneous metastases from other breast carcinomas may present as nodules, erythematous plaques, or inflammatory reactions.
View Article and Find Full Text PDFSarcoidosis is an immune-mediated multisystem condition of unknown etiology, characterized by non-caseating granulomatous inflammation. While it commonly affects the lungs and the reticuloendothelial system, it can affect any organ. Most of such cases involve the central nervous system, but the condition rarely presents with symptoms related to hypothalamic-pituitary dysfunction.
View Article and Find Full Text PDFJ Cutan Pathol
December 2024
Department of Medicine, Division of Dermatology, St. Louis School of Medicine, Washington University, St. Louis, Missouri, USA.
Angiosarcoma is a rare and aggressive malignancy of endothelial cells with multiple subtypes. Foamy cell angiosarcoma is a rare variant in which endothelial cells demonstrate "foamy" cytoplasmic change. We present the case of a 59-year-old male who presented with progressive erythema and swelling of the midface and bilateral eyelids.
View Article and Find Full Text PDFIndian Dermatol Online J
October 2024
Department of Dermatology and Venereology, AIIMS, New Delhi, India.
Nontuberculous mycobacterial (NTM) infections are increasingly recognized, particularly in tropical regions and are often found in immunocompetent individuals. These infections are emerging as significant health concerns, especially pulmonary NTM, which is reported more frequently and is known to be associated with hospital environments. While pulmonary NTM infections are on the rise, partly due to drug resistance and possible patient-to-patient transmission, there is no current evidence indicating an increase in cutaneous NTM infections.
View Article and Find Full Text PDFJ Cutan Pathol
December 2024
Department of Dermatology, Brown University School of Medicine, Providence, Rhode Island, USA.
Erythema nodosum leprosum (ENL) is an immune complex-mediated response in Mycobacterium leprae infection, presenting with fever, arthralgias, and tender cutaneous lesions. It mimics Sweet syndrome (SS) clinically and histologically but requires distinct management. A 65-year-old man with recent travel presented with fever and edematous plaques.
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