https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=36091620&retmode=xml&tool=Litmetric&email=readroberts32@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09 3609162020220913
1878-54092632022SepJournal of cardiology casesJ Cardiol CasesLow-molecular-weight dextran-induced anaphylactic shock immediately after intracoronary imaging.229231229-23110.1016/j.jccase.2022.05.003Dextran has been frequently used during intracoronary imaging, such as in optical coherence tomography, optical frequent domain imaging, and coronary angioscopy. We report a case of dextran-induced anaphylaxis in a 70-year-old male with chronic coronary disease. Upon admission, we performed coronary angiography and coronary angioscopy on the patient. After the intracoronary imaging, the patient's blood pressure suddenly fell to 50 mmHg and a rash appeared on his chest. The patient was diagnosed as having dextran-induced anaphylactic shock. Epinephrine was administered repeatedly, and his blood pressure gradually recovered after administering a total of 6 mg epinephrine. There was no recurrence of the anaphylactic shock, and the patient was discharged 12 days later. The incidence of dextran-induced anaphylactic reactions is extremely low; however, they can be fatal. The possibility of anaphylactic shock induced by dextran should be kept in mind by all cardiovascular interventionalists performing intracoronary imaging.Dextran has been frequently used during intracoronary imaging. We report on a case of dextran-induced anaphylaxis in a 70-year-old male with chronic coronary disease. While the incidence of dextran-induced anaphylactic reactions is extremely low, it can lead to fatal events. The possibility of anaphylactic shock induced by dextran should be kept in mind by all cardiovascular interventionalists while performing intracoronary imaging.© 2022 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved. All rights reserved.DaiKazuokiKDepartment of Cardiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.OiKuniomiKDepartment of Cardiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.HyodoYoheiYDepartment of Cardiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.JyuriYusukeYDepartment of Cardiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.TakayamaShinSDepartment of Cardiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.ShigeharaMikioMDepartment of Cardiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.TomomoriShunsukeSDepartment of Cardiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.HigakiTadanaoTDepartment of Cardiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.KawaseTomoharuTDepartment of Cardiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.SuenariKazuyoshiKDepartment of Cardiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.NishiokaKenjiKDepartment of Cardiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.OtsukaMasayaMDepartment of Cardiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.MasaokaYoshikoYDepartment of Cardiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.ShiodeNobuoNDepartment of Cardiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.NakanoYukikoYDepartment of Cardiovascular Medicine, Division of Medicine, Biomedical Sciences Major, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.engCase Reports20220604
JapanJ Cardiol Cases1015495791878-5409AnaphylaxisCoronary angioscopyDextranThere is no conflict of interest related to this manuscript.
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