AI Article Synopsis
- - A female patient in her sixties with overactive bladder experienced a decline in bladder compliance after receiving botulinum toxin type A and stopping her medication.
- - The patient had a history of surgeries for spinal issues and had been on a combination of treatments for her bladder condition prior to the injection.
- - After three months post-injection, complications like renal dysfunction and hydronephrosis occurred, but her condition improved when she restarted her medications and used a temporary catheter.
Article Abstract
Introduction: We report a case of deterioration of bladder compliance after botulinum toxin type A injection and discontinuation of medication for overactive bladder.
Case Presentation: A female patient with overactive bladder in her sixties had been visiting our outpatient clinic regularly for 4 years. She had received posterolateral spondylus fusion twice, which resulted in a compression fracture. She had been receiving a combination therapy of anticholinergics and β3-adrenoceptor agonist for the management of overactive bladder. She received botulinum toxin type A injection for refractory overactive bladder and discontinued medical treatment for overactive bladder. Three months after botulinum toxin type A injection, cystometry revealed the deterioration of bladder compliance. Renal dysfunction, hydronephrosis, and vesicoureteral reflux were shown. Renal function and hydronephrosis were improved after restarting anticholinergics and β3-adrenoceptor agonist therapy and inserting a temporary transurethral catheter.
Conclusion: Deterioration of bladder compliance may occur after botulinum toxin type A injection and discontinuation of overactive bladder medication in some patients with underlying neurological disease.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436694 | PMC |
| http://dx.doi.org/10.1002/iju5.12496 | DOI Listing |
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