Introduction: The modified Ferriman-Gallwey (mFG) scale is accepted as a useful clinical scoring system in the evaluation of hirsutism.
Aim: To prevent overlooking hirsutism diagnoses and facilitate patient examinations in ongoing pandemic conditions by simplifying the mFG score.
Material And Methods: This study included 227 patients who were diagnosed with hirsutism and had mFG scores of ≥ 8. Hair distribution and hair growth intensity of nine different body regions in the mFG score were examined.
Results: Among our patients with hirsutism, terminal hair was present on the chin in 97.4% ( = 221), thighs in 96.5% ( = 219), upper lip in 94.7% ( = 215), and lower abdomen in 92.1% ( = 205), and this was significantly higher compared with the remaining five regions ( < 0.001 for each comparison). Terminal hair growth scored as ≥ 1 was found in 89% of the patients ( = 202) for the combination of the chin, thighs, and upper lip, and in 87.2% ( = 198) for the combination of the chin, thighs, and lower abdomen. When the chin and thighs were evaluated together, 75.3% ( = 171) of the patients had ≥ 2 terminal hair growth.
Conclusions: In addition to the chin and thighs being the main regions of terminal hair growth, examination of the upper lip or lower abdomen can sufficiently help predict hirsutism. During the ongoing pandemic conditions when we need to follow social distancing rules, a practical approach to the mFG scoring system will facilitate the work of many physicians, including dermatologists, and will shorten the patient's stay in the clinic.
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http://dx.doi.org/10.5114/ada.2021.108455 | DOI Listing |
Methods Mol Biol
December 2024
University of California - Davis, Department of Environmental Toxicology, Davis, CA, USA.
Hair is a ubiquitous and robust mammalian tissue with biological, clinical, forensic, social, and economic significance. The hair shaft proteome reflects both structural proteins, dominated by cuticular intermediate filament keratins and associated proteins, and proteins involved in the final cellular processes of terminally differentiating corneocytes prior to cornification. These distinct biological processes involve cell maintenance, biosynthesis, senescence, and xenobiotic response.
View Article and Find Full Text PDFHear Res
December 2024
Eaton-Peabody Laboratories, Massachusetts Eye and Ear, Boston, MA, United States; Department of Otolaryngology-Head & Neck Surgery, Harvard Medical School, Boston, MA, United States. Electronic address:
Auditory-nerve fibers (ANFs) from a given cochlear region can vary in threshold sensitivity by up to 60 dB, corresponding to a 1000-fold difference in stimulus level, although each fiber innervates a single inner hair cell (IHC) via a single synapse. ANFs with high-thresholds also have low spontaneous rates (SRs) and synapse on the side of the IHC closer to the modiolus, whereas the low-threshold, high-SR fibers synapse on the side closer to the pillar cells. Prior biophysical work has identified modiolar-pillar differences in both pre- and post-synaptic properties, but a comprehensive explanation for the wide range of sensitivities remains elusive.
View Article and Find Full Text PDFJ Craniofac Surg
December 2024
Department of Plastic and Reconstructive Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China.
Following facial reconstruction with a scalp flap, unwanted hair is a common esthetic problem. Reports on the safety, effectiveness, and differences in laser hair removal before, during, and after tissue expansion are lacking. The authors aimed to assess the efficacy of 800-nm diode laser hair removal before, during, and after flap expansion.
View Article and Find Full Text PDFBiochim Biophys Acta Mol Basis Dis
December 2024
Otorhinolaryngology Hospital, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China; Institute of Otorhinolaryngology, Sun Yat-sen University, Guangzhou 510080, China. Electronic address:
Auditory neuropathy (AN) is an under-recognized form of hearing loss characterized by lesions in inner hair cells (IHCs), ribbon synapses and spiral ganglion neurons (SGNs). The lack of a targeted therapy for AN has increased the need for a better understanding of the pathogenic mechanism of AN. As mitogen-activated protein kinase (MAPK) signaling is ubiquitous in many biological processes, its alteration may facilitate the pathogenesis of multiple sites in AN.
View Article and Find Full Text PDFFront Neurol
November 2024
Caruso Department of Otolaryngology-Head and Neck Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States.
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