AI Article Synopsis

  • * A case study involved a 74-year-old woman whose MAC-PD treatment was ineffective, prompting further testing that revealed a co-infection, which was successfully treated with trimethoprim-sulfamethoxazole (TMP-SMX).
  • * The findings emphasize that worsening chest CT results after adequate MAC-PD treatment may indicate other infections, highlighting the need to differentiate these conditions in immunocompetent patients.

Article Abstract

pulmonary disease (MAC-PD) is sometimes accompanied by co-infection with other pathogenic microorganisms such as and . However, co-infection with spp. has been rarely reported. We report on a patient diagnosed as having co-infection with after treatment for MAC-PD, which was successfully treated using trimethoprim-sulfamethoxazole (TMP-SMX). A 74-year-old woman with MAC-PD was admitted to our hospital to undergo re-examination for pathogenic microorganisms because chest computed tomography (CT) findings did not improve after treatment for MAC-PD. She underwent bronchoscopy and was detected from bronchoalveolar lavage fluid culture. Chest CT findings improved after 6 months of treatment using TMP-SMX. Co-infection with other pathogenic microorganisms should be considered when chest CT findings worsen after adequate treatment of MAC-PD. Chest CT findings of pulmonary disease in immunocompetent patients can mimic those of MAC-PD and should therefore be differentiated one from the other.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9452899PMC
http://dx.doi.org/10.1002/rcr2.1036DOI Listing

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