AI Article Synopsis
- Hemophagocytic syndrome is a rare, severe disorder often triggered by conditions like HIV or opportunistic infections, causing serious health risks.
- A case is presented involving a patient with severe hemophagocytic syndrome due to disseminated toxoplasmosis, leading to multiple organ failure while in the ICU.
- The patient received treatment with etoposide and specific anti-toxoplasmosis therapy, ultimately recovering with minimal lasting effects, highlighting the need for quick diagnosis and treatment in similar cases.
Article Abstract
Hemophagocytic syndrome is a rare life-threatening disorder that can be triggered by various conditions such as HIV infection and opportunistic agents. We report a case of disseminated toxoplasmosis complicated with severe hemophagocytic syndrome and revealing an unknown acquired immunodeficiency syndrome. The patient presented with multiple organ failure in intensive care unit. Once diagnosed, he benefitted from etoposide infusion, administration of specific anti-toxoplasmosis treatments and secondary antiretroviral therapy. He was alive at intensive care unit discharge and returned home with little sequalae. This case illustrates both the importance of rapid investigations of hemophagocytic syndrome etiologies in HIV positive patients and the necessity to prompt etoposide and specific treatments in order to improve potentially dramatic outcomes.
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| http://dx.doi.org/10.1016/j.revmed.2022.07.016 | DOI Listing |
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