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| http://dx.doi.org/10.5694/mja2.51699 | DOI Listing |
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Surgical correction of a chin-on-abdomen deformity due to ankylosing spinal deformity and obesity: illustrative case.
J Neurosurg Case Lessons
January 2025
Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois.
Background: Kyphotic spinal deformity is a complication of ankylosing spondylitis (AS). In rare cases, particularly in obese patients, the deformity might extend to the cervicothoracic spine, resulting in a severe "chin-on-abdomen" deformity. This condition severely impairs quality of life by affecting gaze, swallowing, and causing chronic pain.
View Article and Find Full Text PDFPatient Factors Influence Minimal Clinically Important Difference for the SNOT-22 in Medically Treated Chronic Rhinosinusitis.
Int Forum Allergy Rhinol
January 2025
Department of Otolaryngology-Head and Neck Surgery, University of Washington, Seattle, Washington, USA.
Background: The present study explores the effect of sociodemographics and comorbidities on the calculated minimal clinically important difference (MCID) for 22-item Sinonasal Outcome Test (SNOT-22) scores in patients with medically treated chronic rhinosinusitis (CRS). The importance of delineating a threshold to indicate clinically meaningful changes perceived by a patient is well acknowledged, yet the influence of patient-specific factors on MCID has not been fully elucidated.
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The synergistic effects of microcredit access and agricultural technology adoption on maize farmer's income in Kenya.
PLoS One
January 2025
Commercialization Division, CSIR-Soil Research Institute, Kumasi, Ghana.
Addressing global food security demands urgent improvement in agricultural productivity, particularly in developing economies where market imperfections are perverse and resource constraints prevail. While microcredit is widely acknowledged as a tool for economic empowerment, its role in facilitating agricultural technology adoption and improving agricultural incomes remains underexplored. This study examines the synergistic effects of microcredit access and agricultural technology adoption on the incomes of maize farmers in Kenya.
View Article and Find Full Text PDFIsoferulic acid facilitates effective clearance of hypervirulent Klebsiella pneumoniae through targeting capsule.
PLoS Pathog
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Department of Respiratory Medicine, Center for Pathogen Biology and Infectious Diseases, Key Laboratory of Organ Regeneration and Transplantation of the Ministry of Education, The First Hospital of Jilin University, Changchun, China.
Hypervirulent Klebsiella pneumoniae (hvKP) poses an alarming threat in clinical settings and global public health owing to its high pathogenicity, epidemic success and rapid development of drug resistance, especially the emergence of carbapenem-resistant lineages (CR-hvKP). With the decline of the "last resort" antibiotic class and the decreasing efficacy of first-line antibiotics, innovative alternative therapeutics are urgently needed. Capsule, an essential virulence determinant, is a major cause of the enhanced pathogenicity of hvKP and represents an attractive drug target to prevent the devastating clinical outcomes caused by hvKP infection.
View Article and Find Full Text PDFShort-Term Effects of Semi-Occluded Vocal Tract Therapy on the Phonation of Children With Vocal Fold Nodules: A Randomized Controlled Trial.
J Speech Lang Hear Res
January 2025
Center for Speech and Language Sciences, Department of Rehabilitation Sciences, Ghent University, Belgium.
Purpose: The aim was to determine and compare the short-term effects of two intensive semi-occluded vocal tract (SOVT) programs, "straw phonation" (SP) and "resonant voice therapy" (RVT), on the phonation of children with vocal fold nodules.
Method: A pretest-posttest randomized controlled study design was used. Thirty children aged 6-12 years were randomly assigned to the SP group ( = 11), RVT group ( = 11), or control group receiving indirect treatment ( = 8) for their voice problems.
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