Multi-class segmentation of vertebrae and inter-vertebral discs (IVDs) is crucial for the diagnosis and treatment of spinal diseases. However, it is still a challenge due to similarities between neighboring vertebrae of a subject and differences among the IVDs from different subjects. In this paper, we propose a novel spine segmentation framework to achieve automatic segmentation of vertebrae and IVDs in MR images. The core component of the new framework is a Multi-View GCN (MVGCN), which utilizes multi-view features and graph convolutional network (GCN) to reason about the relations of vertebrae and IVDs. We additionally use a boundary constraint for better segmentation of the boundary between vertebrae and IVDs. We test our method on a public spine dataset of 172 MR volumetric images for the vertebrae and IVDs segmentation. The experimental results demonstrate the efficacy of our method. Code and models of our method will be available in the future.
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http://dx.doi.org/10.1109/EMBC48229.2022.9871222 | DOI Listing |
3D Print Med
January 2025
Musculoskeletal Biomechanics Research Lab, Department of Mechanical Engineering, McGill University, 845 Sherbrooke St. W (163), Montréal, QC, H3A 0C3, Canada.
Background: There exists a need for validated lumbar spine models in spine biomechanics research. Although cadaveric testing is the current gold standard for spinal implant development, it poses significant issues related to reliability and repeatability due to the wide variability in cadaveric physiologies. Moreover, there are increasing ethical concerns with human dissection practices.
View Article and Find Full Text PDFAnn Med
December 2025
Department of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, The People's Republic of China.
Objectives: The incidence rate of intervertebral disc degeneration (IVDD) is increasing year by year, which brings great harm to our health. The change of biomechanical factors is an important reason for IVDD. Therefore, more and more studies use finite element (FE) models to analyze the biomechanics of spine.
View Article and Find Full Text PDFFront Bioeng Biotechnol
January 2025
Institute for Neuroradiology, TUM University Hospital, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Introduction: Biomechanical simulations can enhance our understanding of spinal disorders. Applied to large cohorts, they can reveal complex mechanisms beyond conventional imaging. Therefore, automating the patient-specific modeling process is essential.
View Article and Find Full Text PDFSpine J
January 2025
Department of Anatomy, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Cheras 56000, Kuala Lumpur, Malaysia; CÚRAM Research Ireland Centre for Medical Devices, School of Medicine, University of Galway, Galway H91 W2TY, Ireland. Electronic address:
Intervertebral disc (IVD) degeneration is a major cause of low back pain (LBP), which results in disability worldwide. However, the pathogenesis of IVD degeneration mediating LBP remains unclear. Current conservative treatments and surgical interventions are both to relieve the symptoms and minimise pain; nevertheless, they are unable to reverse the degeneration.
View Article and Find Full Text PDFAnimal Model Exp Med
January 2025
Department of Orthopaedic Surgery, The 909th Hospital, School of Medicine, Xiamen University, Zhangzhou, China.
Backgroud: Intervertebral disc degeneration (IDD) is one of the common degenerative diseases. Due to ethical constraints, it is difficult to obtain sufficient research on humans, so the use of an animal model of IDD is very important to clarify the pathogenesis and treatment mechanism of the disease.
Methods: In this study, thirty 2-month-old mice were selected for operation to establish a coccygeal IDD model.
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