Deep learning based medical image segmentation is currently a widely researched topic. Attention mechanism used with deep networks significantly benefit semantic segmen-tation tasks. The recent criss-cross-attention module captures global self-attention while remaining memory and time efficient. However, capturing attention from only the pertinent non-local locations can cardinally boost the accuracy of semantic segmentation networks. We propose a new Deformable Attention Network (DANet) that enables a more accurate contextual information computation in a similarly efficient way. Our novel technique is based on learning the deformation of the query, key and value attention feature maps in a continuous way. A deep segmentation network with this attention mechanism is able to capture attention from germane non-local locations. This boosts the segmentation performance of COVID-19 lesion segmentation compared to criss-cross attention within aU-Net. Our validation experiments show that the performance gain of the recursively applied deformable attention blocks comes from their ability to capture dynamic and precise (wider) attention context. DANet achieves Dice scores of 60.17% for COVID-19 lesions segmentation and improves the accuracy by 4.4% points compared to a baseline U-Net.
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http://dx.doi.org/10.1109/EMBC48229.2022.9871439 | DOI Listing |
Expert Rev Anticancer Ther
January 2025
School of Pharmaceutical Sciences, Lovely Professional University, Jalandhar - Delhi, Punjab, India.
Introduction: Acute Myeloid Leukemia is a heterogeneous hematological malignancy characterized by the uncontrolled proliferation of abnormal myeloid cells. Besides several other genetic abnormalities developed in AML, FLT3 mutations are significant due to their worse prognostic impacts and therapeutic resistance. As a result, these mutations enable AML cells to develop mechanisms for evading immune surveillance.
View Article and Find Full Text PDFSci Rep
January 2025
AVIC Beijing Precision Engineering Institute for Aircraft Industry, Aviation Industry Corporation of China, LTD, Beijing, 100076, China.
With the escalating demand for exploration within confined spaces, bionic design methodologies have attracted considerable attention from researchers, primarily due to the intrinsic limitations of human access to hazardous environments. However, contemporary bionic robots primarily attain linear motion through the axial radial deformation of their body segments, thereby lacking the upright functionality that is characteristic of these organisms. In response to the limitations associated with current bionic earthworm robots concerning upright capability and stiffness modulation, we propose an innovative bionic robot that incorporates upright functionality and programmable stiffness.
View Article and Find Full Text PDFNeuroscience
January 2025
Department of Medical Imaging and Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University General Hospital, Tianjin 300052, China. Electronic address:
Abnormal functional and structural connectivity of brain networks is commonly observed in patients with type 2 diabetes mellitus (T2DM) and accompanied bycognitive impairment. In this study, we revealed differences in brain structure in T2DM using a Morphometric Similarity Network (MSN) method, which quantifies structural similarities between brain regions. The associations between T2DM-associated changes in morphometric similarity (MS) and gene expression were analyzed to explore the molecular and cellular mechanism underlying MS changes in T2DM.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Advanced General Dentistry, College of Dentistry, Yonsei University, Seoul, Korea.
Polylactic acid (PLA) has garnered attention for use in interim dental restorations due to its biocompatibility, biodegradability, low cost, ease of fabrication, and moderate strength. However, its performance under intraoral conditions, particularly under heat and moisture, remains underexplored. This study evaluated the mechanical properties of PLA interim crowns compared with those of polymethylmethacrylate (PMMA) and bisphenol crowns under simulated intraoral conditions with thermocycling.
View Article and Find Full Text PDFJ Drug Target
January 2025
School of Stomatology, Wannan Medical College, Wuhu 241000, Anhui, China.
There are 275,000 new cases of oral cancer (OC) per year, making it the sixth most common cancer in the world. Severe adverse effects, including loss of function, deformity, and systemic toxicity, are familiar with traditional therapies such as radiation, chemotherapy, and surgery; due to their unique properties, nanoparticles (NPs) have emerged as a superior alternative over chemo/radiotherapy and surgery due to their targeting capability, bioavailability, compatibility, and high solubility. Due to their unique properties, metallic NPs have garnered significant attention in OC control.
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