The interest in development of methods and tools for recognizing human emotions has increased continuously. Using physiological information, especially the peripheral physiological signals, to identify emotions is an important direction for this area. This paper proposes an approach for emotion recognition based on energy-related features extracted from peripheral physiological signals. Three emotions: calm, happiness and fear, were elicited in 54 volunteers using video clips while three peripheral physiological signals were recorded: Electrocardiography (ECG), Photoplethysmography (PPG) and Respiration. Given that energy-related features of physiological signals are closely related to autonomic nervous systems activities, nine energy-related features were extracted from the recorded physiological signals. To find the optimal feature subset to represent the target emotions, the correlation between features and emotion state, as well as the discrimination ability of feature for emotion recognition were both analyzed. Four optimal features were then selected for further classification. Moreover, models based on Decision Tree (DT) were built to evaluate the performance of these features for purpose of recognition of emotion states of calm, happiness, and fear. The results show that the DT models based on these four optimal features could distinguish fear from calm (AUC=0.879, Accuracy=87.8%), happiness from calm (AUC=0.915, Accuracy=91.8%), and fear from happiness (AUC=0.822, Accuracy=81.8%), with a global recognition accuracy of 70.8%. These results indicate that energy-related features of peripheral physiological signals can reliably identify emotions, especially intense emotions.
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http://dx.doi.org/10.1109/EMBC48229.2022.9871935 | DOI Listing |
JMIR Med Inform
January 2025
School of Software, Taiyuan University of Technology, Jingzhong, China.
Background: The prompt and accurate identification of mild cognitive impairment (MCI) is crucial for preventing its progression into more severe neurodegenerative diseases. However, current diagnostic solutions, such as biomarkers and cognitive screening tests, prove costly, time-consuming, and invasive, hindering patient compliance and the accessibility of these tests. Therefore, exploring a more cost-effective, efficient, and noninvasive method to aid clinicians in detecting MCI is necessary.
View Article and Find Full Text PDFMol Divers
January 2025
Chemometrics and Cheminformatics Laboratory, Department of Analytical Chemistry, Tarbiat Modares University, Tehran, Iran.
Adenosine receptors (A, A, A, A) play critical roles in cellular signaling and are implicated in various physiological and pathological processes, including inflammations and cancer. The main aim of this research was to investigate structure-activity relationships (SAR) to derive models that describe the selectivity and activity of inhibitors targeting Adenosine receptors. Structural information for 16,312 inhibitors was collected from BindingDB and analyzed using machine learning methods.
View Article and Find Full Text PDFCardiovasc Drugs Ther
January 2025
Department of Cardiology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, 16766 Jingshi Road, Jinan City, 250014, China.
Background: Glucagon-like peptide-1 (GLP-1) is a crucial incretin hormone secreted by intestinal endocrine L cells. Given its pivotal physiological role, researchers have developed GLP-1 receptor agonists (GLP-1 RAs) through structural modifications. These analogues display pharmacological effects similar to those of GLP-1 but with augmented stability and are regarded as an effective means of regulating blood glucose levels in clinical practice.
View Article and Find Full Text PDFAnalyst
January 2025
Phase I Clinical Trial Center, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, PR China.
Protein -glycosylation, as one of the most crucial post-translational modifications, plays a significant role in various biological processes. The structural alterations of -glycans are closely associated with the onset and progression of numerous diseases. Therefore, the precise and specific identification of disease-related -glycans in complex biological samples is invaluable for understanding their involvement in physiological and pathological processes, as well as for discovering clinical diagnostic biomarkers.
View Article and Find Full Text PDFNatl Sci Rev
February 2025
Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China.
Organic red/near-infrared (NIR) room-temperature phosphorescence (RTP) holds significant potential for autofluorescence-free bioimaging and biosensing due to its prolonged persistent luminescence and exceptional penetrability. However, achieving activatable red/NIR organic RTP probes with tunable emission in aqueous solution remains a formidable challenge. Here we report on aqueous organic RTP probes with red/NIR phosphorescence intensity and lifetime amplification.
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