AI Article Synopsis
- Current artificial disc prostheses have limited range of motion, prompting the need for a new intervertebral disc design using advanced materials like carbon fiber and hydrogel loaded with stem cells.
- Biomechanical evaluations of the new design showed promising results, indicating it mimics preclinical conditions and possesses the desired mechanical properties for spinal support.
- Traditional surgical treatments for cervical spondylosis often fail to restore full movement and may lead to complications such as fatigue and improper bone attachment, highlighting the importance of improved prostheses.
Article Abstract
Most of the current artificial disc prosthesis presented a restricted range of motion. Here we propose the design of a novel intervertebral disc composed of carbon fiber, hyaluronic methylcellulose hydrogel loaded with mesenchymal stem cells and polycaprolactone. The prosthesis was biomechanically evaluated under two static physiological conditions to study the mechanical influence of the material on the device. The results obtained in the simulations showed a not only a congruent behavior with preclinical condition, but also that the proposed materials met the desired biomechanical properties Clinical Relevance- Cervical spondylosis is a degenerative disease of the human spine that causes wear and tear of the cervical intervertebral discs. Nowadays, the proposed surgical solutions do not allow fully recovery of normal movement because the surgical intervention do not emulate the natural range of motion, may lack shock absorption mechanisms, show signs of fatigue over time affecting its durability, and do not have good bone adhesion. Therefore, hypermobility and problems of heterotopic ossification may restrict the range of motion.
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| http://dx.doi.org/10.1109/EMBC48229.2022.9871418 | DOI Listing |
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