Temporal interference (TI) stimulation is a technique in which two high frequency sinusoidal electric fields, oscillating at a slightly different frequency are sent into the brain. The goal is to achieve stimulation at the place where both fields interfere. This study uses a simplified version of the Hodgkin - Huxley model to analyse the different parameters of the TI-waveform and how the neuron reacts to this waveform. In this manner, the underlying mechanism of the reaction of the neuron to a TI -signal is investigated. Clinical relevance- This study shows the importance of the parameter choice of the temporal interference waveform and provides insights into the underlying mechanism of the neuronal response to a beating sine for the application of temporal interference stimulation.
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http://dx.doi.org/10.1109/EMBC48229.2022.9871641 | DOI Listing |
Bio Protoc
January 2025
Department of Biomedicine, University of Bergen, Bergen, Norway.
During neuronal synaptic transmission, the exocytotic release of neurotransmitters from synaptic vesicles in the presynaptic neuron evokes a change in conductance for one or more types of ligand-gated ion channels in the postsynaptic neuron. The standard method of investigation uses electrophysiological recordings of the postsynaptic response. However, electrophysiological recordings can directly quantify the presynaptic release of neurotransmitters with high temporal resolution by measuring the membrane capacitance before and after exocytosis, as fusion of the membrane of presynaptic vesicles with the plasma membrane increases the total capacitance.
View Article and Find Full Text PDFJ Exp Biol
January 2025
Independent researcher, 74 Eccleston Square, London, UK.
The function of zebra stripes has long puzzled biologists: contrasted and conspicuous colours are unusual in mammals. The puzzle appears solved: two lines of evidence indicate that they evolved as a protection against biting flies, the geographical coincidence of stripes and exposure to trypanosomiasis in Africa and field experiments showing flies struggling to navigate near zebras. A logical mechanistic explanation would be that stripes interfere with flies' analysis of the optic flow; however, both spatio-temporal aliasing and the aperture effect seem ruled out following recent experiments showing that randomly checked patterns also interfere with flies' capacity to navigate near zebras.
View Article and Find Full Text PDFSensors (Basel)
January 2025
School of Electronic Engineering, Beijing University of Posts and Telecommunications, Beijing 100876, China.
This research presents an intelligent beam-hopping-based grant-free random access (GFRA) architecture designed for secure Internet of Things (IoT) communications in Low Earth Orbit (LEO) satellite networks. In light of the difficulties associated with facilitating extensive device connectivity while ensuring low latency and high reliability, we present a beam-hopping GFRA (BH-GFRA) scheme that enhances access efficiency and reduces resource collisions. Three distinct resource-hopping schemes, random hopping, group hopping, and orthogonal group hopping, are examined and utilized within the framework.
View Article and Find Full Text PDFSensors (Basel)
December 2024
National Key Laboratory of Shock Wave and Detonation Physics, Institute of Fluid Physics, China Academy of Engineering Physics, Mianyang 622150, China.
An ultrafast microwave ranging method based on optically generated frequency-modulated microwave pulses is proposed in this study. The theoretical analysis demonstrated that nanosecond-scale linear frequency modulation microwave pulse can be obtained by femtosecond laser interference under the condition of unbalanced dispersion, which can be used to achieve a high temporal resolution of the displacement change in the measurement by the principle of frequency modulation continuous wave (FMCW) radar. The proof-of-principle experiment successfully measured the displacement change with an error of 2.
View Article and Find Full Text PDFMidwifery
December 2024
School of Nursing, College of Nursing, Taipei Medical University, Taipei 110301, Taiwan. Electronic address:
Background: Abdominal binders are a prominent non-pharmacological intervention aimed at mitigating adverse outcomes following Cesarean delivery (CD), including pain and distress.
Aim: We conducted a meta-analysis to quantitatively evaluate the effects of abdominal binders on women undergoing CD.
Methods: A systematic search was conducted using terms such as "abdominal binder," "clinical trials," and variations of "cesarean" across multiple electronic databases, including PubMed, Google Scholar, Embase, Cochrane Central Register of Controlled Trials, ClinicalTrials.
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