Craniosynostosis is a condition associated with the premature fusion of skull sutures affecting infants. 3D photogrammetric scans are a promising alternative to computed tomography scans in cases of single suture or nonsyndromic synostosis for diagnostic imaging, but oftentimes diagnosis is not automated and relies on additional cephalometric measure-ments and the experience of the surgeon. We propose an alternative representation of the infant's head shape created from 3D photogrammetric surface scans as 2D distance maps. Those 2D distance maps rely on ray casting to extract distances from a center point to the head surface, arranging them into a 2D image grid. We use the distance map for an original convolutional neural network (CNN)-based classification approach, which is evaluated on a publicly available synthetic dataset for benchmarking and also tested on clinical data. Qualitative differences of different head shapes can be ob-served in the distance maps. The CNN-based classifier achieves accuracies of 100 % on the publicly available synthetic dataset and 98.86 % on the clinical test set. Our distance map approach demonstrates the diagnostic value of 3D photogrammetry and the possibility of automatic, CNN-based diagnosis. Future steps include the improvement of the mapping method and testing the CNN on more pathologies.
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http://dx.doi.org/10.1109/EMBC48229.2022.9871526 | DOI Listing |
Sci Rep
January 2025
Department of Ophthalmology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
To assess the choroidal vessels in healthy eyes using a novel three-dimensional (3D) deep learning approach. In this cross-sectional retrospective study, swept-source OCT 6 × 6 mm scans on Plex Elite 9000 device were obtained. Automated segmentation of the choroidal layer was achieved using a deep-learning ResUNet model along with a volumetric smoothing approach.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA.
Background: Annotation of target genes of non-coding GWAS loci remains a challenge since 1) regulatory elements identified by GWAS can be metabases away from its actual target, 2) one regulatory element can target multiple genes, and 3) multiple regulatory elements can target one gene. AD GWAS in populations with different ancestries have identified different loci, suggesting ancestry-specific genetic risks. To understand the connection between associated loci (potential regulatory elements) and their target genes, we conducted Hi-C analysis in frontal cortex of African American (AA) and Non-Hispanic Whites (NHW) AD patients to map chromatin loops, which often represent enhancer-promoter (EP) interactions.
View Article and Find Full Text PDFSci Rep
January 2025
Civil and Environmental Engineering Department, King Fahd University of Petroleum and Minerals, 31261, Dhahran, Saudi Arabia.
Pollution monitoring in surface water using field observational procedure is a challenging matter as it is time consuming, and needs a lot of efforts. This study addresses the challenge of efficiently monitoring and predicting water pollution using a GIS-based artificial neural network (ANN) to detect heavy metal (HM) pollution in surface water and effect of wastewater required discharge on the Euphrates River in Al-Diwaniyah City, Iraq. The study established using 40 water sampling stations and incorporates Inductively Coupled Plasma Atomic Emission Spectrometry (ICP-OES) to assess HM levels.
View Article and Find Full Text PDFFront Artif Intell
December 2024
Computer Science and Software Engineering Department, Auckland University of Technology, Auckland, New Zealand.
Introduction: Musical instrument recognition is a critical component of music information retrieval (MIR), aimed at identifying and classifying instruments from audio recordings. This task poses significant challenges due to the complexity and variability of musical signals.
Methods: In this study, we employed convolutional neural networks (CNNs) to analyze the contributions of various spectrogram representations-STFT, Log-Mel, MFCC, Chroma, Spectral Contrast, and Tonnetz-to the classification of ten different musical instruments.
Sci Rep
December 2024
School of Population Health, Faculty of Health Sciences, Curtin University, Bentley, WA, Australia.
While bacille-calmette-guerin (BCG) vaccination is one of the recommended strategies for preventing tuberculosis (TB), its coverage is low in several countries, including Ethiopia. This study investigated the spatial co-distribution and drivers of TB prevalence and low BCG coverage in Ethiopia. This ecological study was conducted using data from a national TB prevalence survey and the Ethiopian demographic and health survey (EDHS) to map the spatial co-distribution of BCG vaccination coverage and TB prevalence.
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