Breast Cancer has been the primary reason for mortality in women of age between twenties and sixties worldwide; moreover early detection and treatment provides patients to get absolute treatment and decrease the mortality rate. Furthermore, recent research indicates that most experienced physicians have plenty of limitations, hence the plethora of work has been carried out to develop an automated mechanism of segmentation and classification of affected area and type of cancer; however, it is still considered to be highly challenging due to the variability of tumor in shape, low signal to noise ratio, shape, size and location of tumor. Furthermore, mammographic mass segmentation and detection are performed as a separate task and a convolution neural network is a highly adopted architecture for the same. In this research, we have designed and developed unified CNN architecture to perform the segmentation and detection of a breast mass. The unified-CNN architecture comprises a novel module for convolution which is combined through additional offset. Further RRS aka Random Region Selection mechanism is applied for data augmentation approach and high-level feature map is implied to achieve the high prediction. Furthermore, unified-CNN is evaluated using the metrics like true positive Rate at FPI (False Positive per Image) and Dice Index on INBreast dataset, also comparative analysis is out carried with various existing methodology. Unified-CNN is developed through improvising CNN. It introduces a novel module at the convolution layer to aim for a high-level feature map in order to get a high prediction. RRS (Random Region Selection) algorithm is used as the data augmentation approach to select the boundary region of the affected area; further robust model training is designed and optimized for process to make optimal. Unified-CNN introduces novel module at the convolution layer to aim for high level feature map in order to get high prediction; further ROI pooling is utilized for boundary detection in images.
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http://dx.doi.org/10.1109/EMBC48229.2022.9871866 | DOI Listing |
J Imaging Inform Med
January 2025
Faculty of Medicine and Pharmacy of Rabat, Mohammed V University of Rabat, Rabat, 10000, Morocco.
Gastrointestinal (GI) disease examination presents significant challenges to doctors due to the intricate structure of the human digestive system. Colonoscopy and wireless capsule endoscopy are the most commonly used tools for GI examination. However, the large amount of data generated by these technologies requires the expertise and intervention of doctors for disease identification, making manual analysis a very time-consuming task.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Endocrinology, Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250001, Shandong, China.
Obesity (OB) and atherosclerosis (AS) represent two highly prevalent and detrimental chronic diseases that are intricately linked. However, the shared genetic signatures and molecular pathways underlying these two conditions remain elusive. This study aimed to identify the shared diagnostic genes and the associated molecular mechanism between OB and AS.
View Article and Find Full Text PDFNat Mater
January 2025
Laboratory of Advanced Optoelectronic Materials, Suzhou Key Laboratory of Novel Semiconductor-optoelectronics Materials and Devices, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, China.
Printing of large-area solar panels necessitates advanced organic solar cells with thick active layers. However, increasing the active layer thickness typically leads to a marked drop in the power conversion efficiency. Here we developed an organic semiconductor regulator, called AT-β2O, to tune the crystallization sequence of the components in active layers.
View Article and Find Full Text PDFPLoS One
January 2025
College of Engineering, South China Agricultural University, Guangzhou, China.
In order to address many issues, such as the inconsistent and unreliable seeding process in traditional mechanical garlic seed metering systems (SMS), as well as the lack of ability to monitor the effectiveness of the seeding, a highly accurate electric-driven metering system (EDMS) was developed and created specifically for garlic seed planters. This study provided a description of the overall structure and functioning principle, as well as an analysis of the mechanism for smooth transit and delivery. A combination of an infrared (IR) sensor, Arduino Mega board, stepper motor, speed sensor, and a Wi-Fi module was employed to operate the EDMS, as well as monitor and count the quantity of garlic seeds during the planting process and determine the qualified rate (QR) and missing rate (MR).
View Article and Find Full Text PDFCancer Med
January 2025
Department of Respiratory Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, People's Republic of China.
Background: Lung adenocarcinoma (LUAD) exhibits molecular heterogeneity, with mitochondrial damage affecting progression. The relationship between mitochondrial damage and immune infiltration, and Weighted Gene Co-expression Network Analysis (WGCNA)-derived biomarkers for LUAD classification and prognosis, remains unexplored.
Aims: The objective of our research is to identify gene modules closely related to the clinical stages of LUAD using the WGCNA method.
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