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| http://dx.doi.org/10.21037/gs-22-375 | DOI Listing |
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ALKBH5, an m6A demethylase, attenuates tumor growth and inhibits metastasis in papillary thyroid carcinoma.
Sci Rep
January 2025
Department of Endocrinology, The Second Affiliated Hospital of Fujian Medical University, No. 950 Donghai Street, Fengze District, Quanzhou, 362000, Fujian, China.
The significance of ALKBH5 in erasing mRNA methylation in mRNA biogenesis, decay, and translation control has emerged as a prominent research focus. Additionally, ALKBH5 is associated with the development of numerous human cancers. However, it remains unclear whether ALKBH5 regulates the growth and metastasis of papillary thyroid carcinoma (PTC).
View Article and Find Full Text PDFInfluence of Body Mass Index on the Clinicopathological Features of Papillary Thyroid Carcinoma in a Chinese Population.
Metab Syndr Relat Disord
January 2025
NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, China.
Previous studies suggested a relationship between obesity and a high risk of thyroid cancer. However, the association between high body mass index (BMI) and the aggressiveness of papillary thyroid carcinoma (PTC) is controversial. In this study, we aimed to investigate the impact of excess BMI on histopathologic aggressiveness of PTC in a Chinese population.
View Article and Find Full Text PDFSolid pseudopapillary epithelial neoplasm of the pancreas with liver metastasis.
BMJ Case Rep
January 2025
Department of General Surgery, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, Maharashtra, India.
A girl in early adolescence presented with complaints of abdominal pain lasting for 4 months, along with a palpable lump in the epigastric region. A CT scan revealed a large solid-cystic mass lesion measuring 9.5×10.
View Article and Find Full Text PDFDiagnostic performance of dual-energy computed tomography (DECT) quantitative parameters for detecting metastatic cervical lymph nodes in patients with papillary thyroid cancer: A systematic review and meta-analysis.
Eur J Radiol
January 2025
Department of Radiology, Hebei General Hospital, 348 Heping West Road, Shijiazhuang 050051, Hebei, China. Electronic address:
Purpose: This study systematically evaluated the diagnostic performance of dual-energy computed tomography (DECT) quantitative parameters in detecting cervical lymph node metastasis in patients with papillary thyroid cancer (PTC).
Method: We searched PubMed, Embase, Web of Science, Cochrane Library, China National Knowledge Infrastructure, and Wanfang Data databases for relevant original studies from database inception to March 2024. The quality of the included studies was evaluated using the QUADAS-2 tool.
Neural Network and Logistic Regression Models Based on Ultrasound Radiomics and Clinical-Pathological Features to Predict Occult Level II Lymph Node Metastasis in Papillary Thyroid Carcinoma.
Acad Radiol
January 2025
Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China (J-W.F., H.L.); Zhejiang Engineering Research Center of Cognitive Healthcare, Sir Run Run Shaw Hospital,School of Medicine, Zhejiang University, Hangzhou, China (H.L.); College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, China (H.L.). Electronic address:
Rationale And Objectives: Papillary thyroid carcinoma (PTC) often metastasizes to lateral cervical lymph nodes, especially in level II. This study aims to develop predictive models to identify level II lymph node metastasis (LNM), guiding selective neck dissection (SND) to minimize unnecessary surgery and morbidity in low-risk patients.
Methods: A retrospective cohort of 313 PTC patients who underwent modified radical neck dissection (MRND) between October 2020 and January 2023 was analyzed.
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