), a wild vegetable with a number of health claims, has been mostly ignored and unexplored. The study aims to compare the nutritional, phytochemical as well as antidiabetic potential of fresh as well as shade-dried leaves of in order to recommend its best form as a dietary antidiabetic product. The results revealed that as compared to fresh leaves, the shade-dried leaves, in addition to possessing higher levels of carbohydrates, crude protein, crude fat, crude fiber, etc., also contain appreciable amounts of total phenols (5833.12 ± 4.222 mg/100), total flavonoids (188.84 ± 0.019 mg/100 g), ascorbic acid (34.70 ± 0.026 mg/100 g), β-carotene (3.88 ± 1.473 mg/100 g) and total chlorophyll (239.51 ± 0.015 mg/100 g) antioxidants. The study revealed the presence of medicinally important antidiabetic flavonoid quercetin present in leaves. Among the three solvent systems used, the aqueous extract of shade-dried leaves comparatively demonstrated potent antidiabetic activity under in vitro conditions in a dose-dependent manner via targeting α-amylase and α-glucosidase, the two potent enzymes of carbohydrate metabolism. Therefore, in addition to being a nutritious herb, the shade-dried leaves of have great potential to suppress post-prandial glucose rise and can be better exploited through clinical trials to be used as a dietary intervention for better management of diabetes.
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http://dx.doi.org/10.3390/molecules27175380 | DOI Listing |
Cureus
August 2024
Nanobiomedicine, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Background And Aim: Dental caries, primarily caused by and Lactobacillus spp., is a major global health issue. There is a growing need for effective, natural antimicrobial treatments.
View Article and Find Full Text PDFFront Plant Sci
August 2024
Division of Agricultural Chemicals, ICAR-Indian Agricultural Research Institute, New Delhi, India.
Fall armyworm (FAW), (J.E. Smith), a threat to maize production systems, is a polyphagous pest of global significance.
View Article and Find Full Text PDFJ Pharm Bioallied Sci
April 2024
Department of Oral Pathology and Microbiology, Royal Dental College, Chalissery, Palakkad, Kerala, India.
Cancer is a disease resulting from the disruption of cell cycle regulation, leading to the abnormal and unchecked proliferation of cells. Medicinal plants are rich in various bioactive phytochemicals or nutritional compounds. The aim is to determine the cytotoxic and genotoxic effects of ethanolic extracts of leaves on human oral cancer cell lines.
View Article and Find Full Text PDFNarra J
December 2023
Division of Pathology, ICAR-Indian Veterinary Research Institute, Bareilly, India.
is a native plant to India's tropical and subtropical regions and has been used as a traditional medicinal. The aim of study was to identify and evaluate the antimicrobial and anti-arthritis activities of hydroethanolic extract of leaves (HEERE). The leaves were collected from the Narkanda Valley, India and were shade-dried and finely ground to produce the powder.
View Article and Find Full Text PDFACS Omega
February 2024
Department of Zoology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
(Fresen.) Gilg has demonstrated significant anticancer potential through multiple mechanisms, including apoptosis induction, as shown by the TUNEL assay against MCF-7 cells, modulation of tubulin polymerization, preservation of mitochondrial function indicated by the JC-1 assay, and inhibition of DNA polymerase α and β activities. Rationale for the present study is to investigate the potential anticancer properties of leaf alkaloid extract.
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