In this study, nanofibers of poly (acrylic acid) (PAAc), polyacrylamide (PAAm) and poly (vinyl alcohol) (PVOH) were prepared using the electrospinning technique. Based on the Taguchi DOE (design of experiment) method, the effects of electrospinning parameters, i.e., needle tip to collector distance, polymer solution concentration, applied voltage, polymer solution feed rate and polymer type, on the diameter and morphology of polymer nanofibers were evaluated. Analyses of the experiments for the diameters of the polymer nanofibers showed that the type of polymer was the most significant factor. The optimal combination to obtain the smallest diameters with minimum deviations for electrospun polymer nanofibers was also determined. For this purpose, the appropriate factor levels were determined as follows: polymer PAAm, applied voltage 10 kV, delivery rate 0.1 mL/h, needle tip to collector distance 10 cm, and polymer solution concentration 8%, to obtain the thinnest nanofibers. This combination was further validated by conducting a confirmation experiment, and the average diameter of the polymer nanofibers was found to be close to the optimal conditions estimated by the Taguchi DOE method.
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http://dx.doi.org/10.3390/ma15175876 | DOI Listing |
Nanoscale Adv
December 2024
School of Engineering and Sciences, Tecnologico de Monterrey Monterrey 64849 Nuevo León Mexico
Liposomes are employed for the delivery of molecular cargo in several classes of systems. For instance, the embedding of loaded liposomes in polymeric fibrous scaffolds has enabled the creation of hybrid materials that mimic biological membranes. Liposomes with unmodified surfaces have been predominantly integrated into fibers, which leads to instabilities due to interfacial incompatibility.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Materials Science and Engineering, Faculty of Engineering, Çanakkale Onsekiz Mart Universitesi, 17100, Çanakkale, Turkey.
The anisotropic behavior of fiber-reinforced polymer composites, coupled with their susceptibility to various failure modes, poses challenges for their structural health monitoring (SHM) during service life. To address this, non-destructive testing techniques have been employed, but they often suffer from drawbacks such as high costs and suboptimal resolutions. Moreover, routine inspections fail to disclose incidents or failures occurring between successive assessments.
View Article and Find Full Text PDFBiomacromolecules
January 2025
Department of Hepatobiliary Surgery, Hebei International Joint Research Center for Digital Twin Diagnosis and Treatment of Digestive Tract Tumors, Baoding Key Laboratory of Precision Diagnosis and Treatment of Digestive Tract Tumors, Affiliated Hospital of Hebei University, Baoding 071000, China.
Friction is the trigger cause for excessive exogenous adhesion, leading to the poor self-repair of the tendon. To address this problem, we developed electrospun dual-functional nanofibers with surface robust superlubricated performance and bioactive agent delivery to regulate healing balance by reducing exogenous adhesion and promoting endogenous healing. Coaxial electrospinning and our previous developed in situ robust nanocoating growth techniques were employed to create the lubricative/repairable core-shell structured nanofibrous membrane (L/R-NM).
View Article and Find Full Text PDFSci Bull (Beijing)
January 2025
Mechanical and Construction Engineering, Faculty of Engineering and Environment, Northumbria University, Newcastle Upon Tyne, NE1 8ST, UK.
With the rapid progress of aerospace frontier engineering, the extreme space thermal environment has brought severe challenges to astronauts' space suits, putting forward higher requirements for thermal protection materials. On this basis, a unique core-shell structured hexagonal boron nitride (h-BN)/silicon dioxide (SiO) nanofiber membrane (HS) was prepared using the coaxial electrospinning method, of which both the thermal insulation SiO nanofiber cortex and the passive radiation cooling (PRC) h-BN nanofiber core make it a promising dual-effect thermal management material. Especially, when the amount of h-BN is 0.
View Article and Find Full Text PDFInt J Pharm
January 2025
Nanostructure and Biomimetic Lab, Department of Nanotechnology, University of Kashmir, Hazratbal, Srinagar 190006, Jammu and Kashmir, India. Electronic address:
The second most prevalent cause of mortality among women is breast cancer, and paclitaxel (PTX) is an effective drug for its treatment. The present work aims to develop patch-based poly(ε-caprolactone) (PCL) nanofibers incorporating PTX as a localized and sustained drug delivery system. The co-deposition of poly(vinyl alcohol) (PVA) fibers during electrospinning was allowed to improve water absorption by the scaffold, which in turn facilitated the release of drug molecules.
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