Sjögren Syndrome: New Insights in the Pathogenesis and Role of Nuclear Medicine.

J Clin Med

Nuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, Faculty of Medicine and Psychology, "Sapienza" University, 00185 Rome, Italy.

Published: September 2022

In the last years, new insights into the molecular basis of rheumatic conditions have been described, which have generated particular interest in understanding the pathophysiology of these diseases, in which lies the explanation of the diversity of clinical presentation and the difficulty in diagnostic and therapeutic approaches. In this review, we focus on the new pathophysiological findings for Sjögren syndrome and on the derived new SPECT and PET radiopharmaceuticals to detect inflammation of immunological origin, focusing on their role in diagnosis, prognosis, and the evaluation of therapeutic efficacy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456759PMC
http://dx.doi.org/10.3390/jcm11175227DOI Listing

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