Safety of Nonagenarians Receiving Therapeutic ERCP, Single Center Experience.

J Clin Med

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung 40705, Taiwan.

Published: September 2022

AI Article Synopsis

  • - The study aimed to understand if nonagenarians (90+) have a higher risk of complications from therapeutic endoscopic retrograde cholangiopancreatography (ERCP) compared to younger adults (ages 65-89).
  • - Researchers analyzed data from patients at Taichung Veterans General Hospital between 2011 and 2016, finding no significant difference in complication rates between the two age groups, although advanced age and end-stage renal disease (ESRD) were identified as risk factors.
  • - The conclusions suggest that while nonagenarians do not have higher complication rates than those under 90, older age and existing health issues like ESRD can still negatively impact the success of ERCP procedures in elderly patients. *

Article Abstract

(1) Background: The complication rates for nonagenarians receiving therapeutic endoscopic retrograde cholangiopancreatography (ERCP) remain poorly understood. We aimed to determine whether nonagenarians were at an increased risk of ERCP-related complications. (2) Methods: We performed a retrospective study on therapeutic ERCP in nonagenarians from 2011 to 2016 at Taichung Veterans General Hospital. A control group comprising patients aged 65 to 89 years was used to compare demographic data and the outcomes of therapeutic ERCP with the nonagenarians. The risk factors for complications were determined by logistic regression model. (3) Results: There were 35 nonagenarians and 111 patients in the control group. Overall, complication rates were not statistically different between the two groups. However, advanced age was an independent predictor of complications in the multivariate analysis (odds ratio [OR] = 1.06; 95% confidence interval [CI] = 1.01-1.12; = 0.049). End stage renal disease (ESRD) was another independent predictor of complications (OR = 4.87; 95% CI = 1.11-21.36; = 0.036). Post-ERCP pancreatitis and bleeding were more common in ESRD patients than patients without ESRD. (4) Conclusions: Although nonagenarians receiving ERCP did not have more complications compared to elderly patients younger than 90 years, advanced age and comorbidity still affect the outcome of therapeutic ERCP in the elderly patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456670PMC
http://dx.doi.org/10.3390/jcm11175197DOI Listing

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