AI Article Synopsis
Article Abstract
Unlabelled: It is necessary to treat neonatal pain because it may have short- and long-term adverse effects. Frenotomy is a painful procedure where sucking, a common strategy to relieve pain, cannot be used because the technique is performed on the tongue. In a previous randomized clinical trial, we demonstrated that inhaled lavender essential oil (LEO) reduced the signs of pain during neonatal frenotomy. We aimed to find out whether inhaled vanilla essential oil (VEO) is more effective in reducing pain during frenotomy than LEO. Randomized clinical trial with neonates who underwent a frenotomy for type 3 tongue-ties between May and October 2021. Pain was assessed using pre and post-procedure heart rate (HR) and oxygen saturation (SatO2), crying time, and NIPS score. Neonates were randomized into "experimental" and "control" group. In both groups, we performed swaddling, administered oral sucrose, and let the newborn suck for 2 min. We placed a gauze pad with one drop of LEO (control group) or of VEO (experimental group) under the neonate's nose for 2 min prior to and during the frenotomy. We enrolled 142 neonates (71 per group). Both groups showed similar NIPS scores (2.02 vs 2.38) and crying times (15.3 vs 18.7 s). We observed no differences in HR increase or in SatO2 decrease between both groups. We observed no side effects in either of the groups.
Conclusions: We observed no appreciable difference between LEO and VEO; therefore, we cannot conclude which of them was more effective in treating pain in neonates who underwent a frenotomy.
Trial Registration: This clinical trial is registered with www.
Clinicaltrials: gov with NCT04867824.
What Is Known: • Pain management is one of the most important goals of neonatal care as it can have long-term neurodevelopmental effects. • Lavender essential oil can help relieve pain due to its sedative, antispasmodic, and anticolic properties.
What Is New: • Lavender and vanilla essential oils are safe, beneficial, easy to use, and cheap in relieving pain in neonates who undergo a frenotomy for type 3 tongue-ties.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458311 | PMC |
| http://dx.doi.org/10.1007/s00431-022-04608-3 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The effect of essential oil on growth performance, immune, antioxidant functions and gut microbiota in pigs.
Front Vet Sci
December 2024
Hunan Provincial Key Laboratory of the Traditional Chinese Medicine Agricultural Biogenomics, Changsha Medical University, Changsha, Hunan, China.
, a perennial herb belonging to the Zingiberaceae family, has a long history of traditional medicinal use. The present study evaluated the efficacy of different concentrations of essential oil (AEO) on the growth performance, serum antioxidation capacities, immune function, apparent digestibility of nutrients, and gut microbiota in fattening pigs. A total of 120 pigs were divided into five treatments, with six replicates each and four pigs per replicate.
View Article and Find Full Text PDFEffect of Balangu seed mucilage/gelatin coating containing dill essential oil and ZnO nanoparticles on sweet cherry quality during cold storage.
Heliyon
December 2024
Department of Food Science and Engineering, Faculty of Agriculture, University of Zanjan, Zanjan, 45371-38791, Iran.
The current research focused on examining the effect of a coating made from Balangu seed mucilage (TSM-BM) and gelatin (Ge), with varying concentrations of dill essential oil (DEO) (0 %, 1 %, and 2 %) and zinc oxide nanoparticles (ZnO-np) (0 % and 0.5 %), on the quality characteristics of cherries stored at 4 °C over intervals of 0, 4, 7, 11, 18, and 25 days. The study noted that the application of this coating, particularly when combined with DEO and ZnO-np, significantly reduced the rate of changes in several parameters, including weight loss, firmness, titratable acidity, pH, total soluble solids, ascorbic acid, total anthocyanin content, total phenolic content, and antioxidant activity (p˂0.
View Article and Find Full Text PDFUse of natural extract from HOP, thyme, orange and algae to protect potatoes against potato blight ().
Heliyon
December 2024
Department of Food Science, Czech University of Life Sciences Prague, Kamycka 129, Prague 6, Czech Republic.
The growing demand for alternative plant protection products (PPP) that are more environmentally friendly leads to the investigation of novel approaches in agriculture. The use of plant extracts as PPP belongs to one of the most intensively investigated areas. This study aimed to evaluate if the partial substitution of conventional pesticides with selected botanicals (seaweed extract, orange essential oil, thyme essential oil, and a hop extract) will have the same protective effect against ans as conventional potato treatment.
View Article and Find Full Text PDFDesign and Characterization of Polyvinyl Alcohol/Kappa-Carrageenan Pickering Emulsion Biocomposite Films for Potential Wound Care Applications.
J Biomed Mater Res A
January 2025
Institute for Fiber Engineering and Science (IFES), Interdisciplinary Cluster for Cutting Edge Research (ICCER), Shinshu University, Ueda, Japan.
This study aimed to develop polyvinyl alcohol (PVA) and kappa-carrageenan (κCA) biocomposite films using a Pickering emulsion technique for wound care applications. Juniper essential oil and modified sepiolite were incorporated to enhance functionality, with films prepared via solvent casting and characterized for structural, thermal, and mechanical properties. The PCOS-2 film exhibited the highest mechanical performance, with Young's modulus of 6.
View Article and Find Full Text PDFCoriander: A holistic outlook on its chemistry and pharmacology.
Food Chem
December 2024
Department of Chemistry, North Eastern Regional Institute of Science and Technology, Nirjuli, Itanagar, Arunachal Pradesh 791109, India. Electronic address:
Coriander (Coriandrum sativum L.) is a nutraceutically renowned annual herb from Apiaceae family and used in cuisines in different countries in different ways to enhance the tastes, flavour and nutritional values of foods. Fruit (seed) has several medicinally valuable chemical components viz.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!